Detalhe da pesquisa
1.
Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis.
EMBO J
; 39(21): e105111, 2020 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32945574
2.
Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma.
Proc Natl Acad Sci U S A
; 116(36): 17990-18000, 2019 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31439820
3.
The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer.
Br J Cancer
; 124(3): 616-627, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33173151
4.
The Potential of Targeting Ribosome Biogenesis in High-Grade Serous Ovarian Cancer.
Int J Mol Sci
; 18(1)2017 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28117679
5.
ß2-adrenoceptor signaling regulates invadopodia formation to enhance tumor cell invasion.
Breast Cancer Res
; 17(1): 145, 2015 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26607426
6.
INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors.
Cancer Discov
; 14(3): 446-467, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38047585
7.
Coronin 1C harbours a second actin-binding site that confers co-operative binding to F-actin.
Biochem J
; 444(1): 89-96, 2012 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22364218
8.
Cystathionine-ß-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation.
Elife
; 112022 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35758651
9.
Regulation of adhesion dynamics by calpain-mediated proteolysis of focal adhesion kinase (FAK).
J Biol Chem
; 285(15): 11418-26, 2010 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-20150423
10.
Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy.
Signal Transduct Target Ther
; 6(1): 323, 2021 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34462428
11.
Type Igamma PIP kinase is a novel uropod component that regulates rear retraction during neutrophil chemotaxis.
Mol Biol Cell
; 18(12): 5069-80, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17928408
12.
Oncogene-induced senescence: From biology to therapy.
Mech Ageing Dev
; 187: 111229, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32171687
13.
A functional genetic screen defines the AKT-induced senescence signaling network.
Cell Death Differ
; 27(2): 725-741, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31285545
14.
CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer.
Nat Commun
; 11(1): 2641, 2020 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32457376
15.
Cystathionine ß-Synthase in Physiology and Cancer.
Biomed Res Int
; 2018: 3205125, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30050925
16.
Integrins in cell migration.
Methods Enzymol
; 426: 47-67, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17697879
17.
Combining High-Content Imaging and Phenotypic Classification Analysis of Senescence-Associated Beta-Galactosidase Staining to Identify Regulators of Oncogene-Induced Senescence.
Assay Drug Dev Technol
; 14(7): 416-28, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27552145
18.
Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling.
Oncotarget
; 7(31): 49800-49818, 2016 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27391441
19.
IL2 Inducible T-cell Kinase, a Novel Therapeutic Target in Melanoma.
Clin Cancer Res
; 21(9): 2167-76, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25934889
20.
LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues.
J Cell Biol
; 207(2): 299-315, 2014 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25349262