Detalhe da pesquisa
1.
Upregulation of the ERRγ-VDAC1 axis underlies the molecular pathogenesis of pancreatitis.
Proc Natl Acad Sci U S A
; 120(20): e2219644120, 2023 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37155882
2.
Noncanonical PDK4 action alters mitochondrial dynamics to affect the cellular respiratory status.
Proc Natl Acad Sci U S A
; 119(34): e2120157119, 2022 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35969774
3.
Inhibition of pyruvate dehydrogenase kinase 4 ameliorates kidney ischemia-reperfusion injury by reducing succinate accumulation during ischemia and preserving mitochondrial function during reperfusion.
Kidney Int
; 104(4): 724-739, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37399974
4.
Estrogen-Related Receptor γ Maintains Pancreatic Acinar Cell Function and Identity by Regulating Cellular Metabolism.
Gastroenterology
; 163(1): 239-256, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35461826
5.
The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptors.
Nat Immunol
; 12(8): 742-51, 2011 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21725320
6.
2-Arachidonoylglycerol ameliorates inflammatory stress-induced insulin resistance in cardiomyocytes.
J Biol Chem
; 292(17): 7105-7114, 2017 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28320859
7.
Human embryonic stem cell-derived cardiomyocytes as an in vitro model to study cardiac insulin resistance.
Biochim Biophys Acta Mol Basis Dis
; 1864(5 Pt B): 1960-1967, 2018 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-29277329
8.
Post-translational modifications of CD36 (SR-B2): Implications for regulation of myocellular fatty acid uptake.
Biochim Biophys Acta
; 1862(12): 2253-2258, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27615427
9.
Small heterodimer partner (SHP) contributes to insulin resistance in cardiomyocytes.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1862(5): 541-551, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28214558
10.
The interaction between AMPKß2 and the PP1-targeting subunit R6 is dynamically regulated by intracellular glycogen content.
Biochem J
; 473(7): 937-47, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26831516
11.
The recruitment of AMP-activated protein kinase to glycogen is regulated by autophosphorylation.
J Biol Chem
; 290(18): 11715-28, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25792737
12.
Cross-talk between two essential nutrient-sensitive enzymes: O-GlcNAc transferase (OGT) and AMP-activated protein kinase (AMPK).
J Biol Chem
; 289(15): 10592-10606, 2014 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-24563466
13.
Activation of cannabinoid receptor type 1 (Cb1r) disrupts hepatic insulin receptor signaling via cyclic AMP-response element-binding protein H (Crebh)-mediated induction of Lipin1 gene.
J Biol Chem
; 287(45): 38041-9, 2012 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22989885
14.
The Role of Pyruvate Metabolism in Mitochondrial Quality Control and Inflammation.
Mol Cells
; 46(5): 259-267, 2023 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36756776
15.
Inhibition of Pyruvate Dehydrogenase Kinase 4 in CD4+ T Cells Ameliorates Intestinal Inflammation.
Cell Mol Gastroenterol Hepatol
; 15(2): 439-461, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36229019
16.
Enhanced Ca2+-channeling complex formation at the ER-mitochondria interface underlies the pathogenesis of alcohol-associated liver disease.
Nat Commun
; 14(1): 1703, 2023 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36973273
17.
Curcumin differentially regulates endoplasmic reticulum stress through transcriptional corepressor SMILE (small heterodimer partner-interacting leucine zipper protein)-mediated inhibition of CREBH (cAMP responsive element-binding protein H).
J Biol Chem
; 286(49): 41972-41984, 2011 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-21994947
18.
Cannabinoid receptor type 1 (CB1R) signaling regulates hepatic gluconeogenesis via induction of endoplasmic reticulum-bound transcription factor cAMP-responsive element-binding protein H (CREBH) in primary hepatocytes.
J Biol Chem
; 286(32): 27971-9, 2011 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21693703
19.
Estrogen-related receptor γ (ERRγ) is a novel transcriptional regulator of phosphatidic acid phosphatase, LIPIN1, and inhibits hepatic insulin signaling.
J Biol Chem
; 286(44): 38035-38042, 2011 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21911493
20.
Transcriptional corepressor SHP recruits SIRT1 histone deacetylase to inhibit LRH-1 transactivation.
Nucleic Acids Res
; 38(14): 4607-19, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20375098