Detalhe da pesquisa
1.
Encoding Allostery in mTOR Signaling: The Structure of the Rag GTPase/Ragulator Complex.
Mol Cell
; 68(5): 823-824, 2017 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29220648
2.
The Inhibitor Endosidin 4 Targets SEC7 Domain-Type ARF GTPase Exchange Factors and Interferes with Subcellular Trafficking in Eukaryotes.
Plant Cell
; 30(10): 2553-2572, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30018156
3.
Nonselective Chemical Inhibition of Sec7 Domain-Containing ARF GTPase Exchange Factors.
Plant Cell
; 30(10): 2573-2593, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30018157
4.
Publisher Correction: PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling.
Nat Chem Biol
; 15(5): 549, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30833779
5.
PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling.
Nat Chem Biol
; 15(4): 358-366, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30742123
6.
Arpin Regulates Migration Persistence by Interacting with Both Tankyrases and the Arp2/3 Complex.
Int J Mol Sci
; 22(8)2021 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33923443
7.
Regulation of small GTPases by GEFs, GAPs, and GDIs.
Physiol Rev
; 93(1): 269-309, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23303910
8.
PAK3 mutations responsible for severe intellectual disability and callosal agenesis inhibit cell migration.
Neurobiol Dis
; 136: 104709, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31843706
9.
Protein-membrane interactions in small GTPase signalling and pharmacology: perspectives from Arf GTPases studies.
Biochem Soc Trans
; 48(6): 2721-2728, 2020 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33336699
10.
Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane.
Proc Natl Acad Sci U S A
; 114(43): 11416-11421, 2017 10 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28923919
11.
Small GTPase peripheral binding to membranes: molecular determinants and supramolecular organization.
Biochem Soc Trans
; 47(1): 13-22, 2019 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30559268
12.
Inhibitory signalling to the Arp2/3 complex steers cell migration.
Nature
; 503(7475): 281-4, 2013 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24132237
13.
Characterization of the activation of small GTPases by their GEFs on membranes using artificial membrane tethering.
Biochem J
; 474(7): 1259-1272, 2017 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28196833
14.
Family-wide Analysis of the Inhibition of Arf Guanine Nucleotide Exchange Factors with Small Molecules: Evidence of Unique Inhibitory Profiles.
Biochemistry
; 56(38): 5125-5133, 2017 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28858527
15.
Structure of the Legionella effector AnkX reveals the mechanism of phosphocholine transfer by the FIC domain.
EMBO J
; 32(10): 1469-77, 2013 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23572077
16.
EFA6 controls Arf1 and Arf6 activation through a negative feedback loop.
Proc Natl Acad Sci U S A
; 111(34): 12378-83, 2014 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25114232
17.
Integrated conformational and lipid-sensing regulation of endosomal ArfGEF BRAG2.
PLoS Biol
; 11(9): e1001652, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24058294
18.
A toxic palmitoylation of Cdc42 enhances NF-κB signaling and drives a severe autoinflammatory syndrome.
J Allergy Clin Immunol
; 146(5): 1201-1204.e8, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32283203
19.
On the use of Legionella/Rickettsia chimeras to investigate the structure and regulation of Rickettsia effector RalF.
J Struct Biol
; 189(2): 98-104, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25498244
20.
A novel membrane sensor controls the localization and ArfGEF activity of bacterial RalF.
PLoS Pathog
; 9(11): e1003747, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24244168