Detalhe da pesquisa
1.
Fragmentation landscape of cell-free DNA revealed by deconvolutional analysis of end motifs.
Proc Natl Acad Sci U S A
; 120(17): e2220982120, 2023 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37075072
2.
The Next Frontier in Noninvasive Prenatal Diagnostics: Cell-Free Fetal DNA Analysis for Monogenic Disease Assessment.
Annu Rev Genomics Hum Genet
; 23: 413-425, 2022 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35316613
3.
Fragmentomics of urinary cell-free DNA in nuclease knockout mouse models.
PLoS Genet
; 18(7): e1010262, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35793278
4.
Epigenetic analysis of cell-free DNA by fragmentomic profiling.
Proc Natl Acad Sci U S A
; 119(44): e2209852119, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36288287
5.
Nuclease deficiencies alter plasma cell-free DNA methylation profiles.
Genome Res
; 31(11): 2008-2021, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34470801
6.
Genome-wide detection of cytosine methylation by single molecule real-time sequencing.
Proc Natl Acad Sci U S A
; 118(5)2021 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33495335
7.
Single-molecule sequencing reveals a large population of long cell-free DNA molecules in maternal plasma.
Proc Natl Acad Sci U S A
; 118(50)2021 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34873045
8.
The Biology of Cell-free DNA Fragmentation and the Roles of DNASE1, DNASE1L3, and DFFB.
Am J Hum Genet
; 106(2): 202-214, 2020 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32004449
9.
Plasma DNA Profile Associated with DNASE1L3 Gene Mutations: Clinical Observations, Relationships to Nuclease Substrate Preference, and In Vivo Correction.
Am J Hum Genet
; 107(5): 882-894, 2020 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33022220
10.
Detection and characterization of jagged ends of double-stranded DNA in plasma.
Genome Res
; 30(8): 1144-1153, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32801148
11.
Fragment Ends of Circulating Microbial DNA as Signatures for Pathogen Detection in Sepsis.
Clin Chem
; 69(2): 189-201, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36576350
12.
Comparison of Single Molecule, Real-Time Sequencing and Nanopore Sequencing for Analysis of the Size, End-Motif, and Tissue-of-Origin of Long Cell-Free DNA in Plasma.
Clin Chem
; 69(2): 168-179, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36322427
13.
Identification and characterization of extrachromosomal circular DNA in maternal plasma.
Proc Natl Acad Sci U S A
; 117(3): 1658-1665, 2020 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31900366
14.
Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin.
Genome Res
; 29(3): 418-427, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30808726
15.
Jagged Ends on Multinucleosomal Cell-Free DNA Serve as a Biomarker for Nuclease Activity and Systemic Lupus Erythematosus.
Clin Chem
; 68(7): 917-926, 2022 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35587043
16.
Single-Molecule Sequencing Enables Long Cell-Free DNA Detection and Direct Methylation Analysis for Cancer Patients.
Clin Chem
; 68(9): 1151-1163, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35587130
17.
Dnase1l3 deletion causes aberrations in length and end-motif frequencies in plasma DNA.
Proc Natl Acad Sci U S A
; 116(2): 641-649, 2019 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30593563
18.
Characteristics of Fetal Extrachromosomal Circular DNA in Maternal Plasma: Methylation Status and Clearance.
Clin Chem
; 67(5): 788-796, 2021 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33615350
19.
Single Cell and Plasma RNA Sequencing for RNA Liquid Biopsy for Hepatocellular Carcinoma.
Clin Chem
; 67(11): 1492-1502, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34463757
20.
Jagged Ends of Urinary Cell-Free DNA: Characterization and Feasibility Assessment in Bladder Cancer Detection.
Clin Chem
; 67(4): 621-630, 2021 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-33604652