Detalhe da pesquisa
1.
Enhancing and monitoring spore production in Clostridium butyricum using pH-based regulation strategy and a robust soft sensor based on back-propagation neural networks.
Biotechnol Bioeng
; 121(2): 551-565, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37921467
2.
An inducible CRISPRi circuit for tunable dynamic regulation of gene expression in Saccharopolyspora erythraea.
Biotechnol Lett
; 46(2): 161-172, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38279045
3.
Ammonium sulfate supplementation enhances erythromycin biosynthesis by augmenting intracellular metabolism and precursor supply in Saccharopolyspora erythraea.
Bioprocess Biosyst Eng
; 46(9): 1303-1318, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37392219
4.
An Efficient High-Throughput Screening of High Gentamicin-Producing Mutants Based on Titer Determination Using an Integrated Computer-Aided Vision Technology and Machine Learning.
Anal Chem
; 94(33): 11659-11669, 2022 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35942642
5.
Comparative genomic and transcriptomic analysis guides to further enhance the biosynthesis of erythromycin by an overproducer.
Biotechnol Bioeng
; 119(6): 1624-1640, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35150130
6.
Cephalosporin C biosynthesis and fermentation in Acremonium chrysogenum.
Appl Microbiol Biotechnol
; 106(19-20): 6413-6426, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-36114850
7.
Engineering of succinyl-CoA metabolism in view of succinylation regulation to improve the erythromycin production.
Appl Microbiol Biotechnol
; 106(13-16): 5153-5165, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35821431
8.
Knockout and functional analysis of BSSS-related genes in Acremonium chrysogenum by novel episomal expression vector containing Cas9 and AMA1.
Biotechnol Lett
; 44(5-6): 755-766, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35526203
9.
Engineering the methyltransferase through inactivation of the genK and genL leads to a significant increase of gentamicin C1a production in an industrial strain of Micromonospora echinospora 49-92S.
Bioprocess Biosyst Eng
; 45(10): 1693-1703, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-36029348
10.
Effect of temperature on synthesis of clavulanic acid and impurity substance G during fermentation by Streptomyces clavuligerus.
Prep Biochem Biotechnol
; 52(8): 937-941, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34871519
11.
Exploring the metabolic fate of propanol in industrial erythromycin-producing strain via 13C labeling experiments and enhancement of erythromycin production by rational metabolic engineering of Saccharopolyspora erythraea.
Biochem Biophys Res Commun
; 542: 73-79, 2021 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33497965
12.
Development of a novel noninvasive quantitative method to monitor Siraitia grosvenorii cell growth and browning degree using an integrated computer-aided vision technology and machine learning.
Biotechnol Bioeng
; 118(10): 4092-4104, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34255354
13.
Exploration and characterization of hypoxia-inducible endogenous promoters in Aspergillus niger.
Appl Microbiol Biotechnol
; 105(13): 5529-5539, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-34254155
14.
In vitro CRISPR/Cas9 system for genome editing of Aspergillus niger based on removable bidirectional selection marker AmdS.
Biotechnol Appl Biochem
; 68(5): 964-970, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32729961
15.
Engineering Pichia pastoris to improve S-adenosyl- l-methionine production using systems metabolic strategies.
Biotechnol Bioeng
; 117(5): 1436-1445, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32027019
16.
Coupled metabolic-hydrodynamic modeling enabling rational scale-up of industrial bioprocesses.
Biotechnol Bioeng
; 117(3): 844-867, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31814101
17.
Improving cytosolic aspartate biosynthesis increases glucoamylase production in Aspergillus niger under oxygen limitation.
Microb Cell Fact
; 19(1): 81, 2020 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32245432
18.
Advances in sophorolipid-producing strain performance improvement and fermentation optimization technology.
Appl Microbiol Biotechnol
; 104(24): 10325-10337, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33097965
19.
A preliminary study on the impact of exogenous A-Factor analogue 1,4-butyrolactone on stimulating bitespiramycin biosynthesis.
Bioprocess Biosyst Eng
; 42(12): 1903-1913, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31471709
20.
Rational high-throughput system for screening of high sophorolipids-producing strains of Candida bombicola.
Bioprocess Biosyst Eng
; 42(4): 575-582, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30680462