Detalhe da pesquisa
1.
Sub-5-min RP-UHPLC-TIMS for high-throughput untargeted lipidomics and its application to multiple matrices.
Anal Bioanal Chem
; 416(4): 959-970, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38078946
2.
In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening.
Int J Mol Sci
; 23(4)2022 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35216186
3.
New Frontiers on ER Stress Modulation: Are TRP Channels the Leading Actors?
Int J Mol Sci
; 24(1)2022 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36613628
4.
In Silico Identification and In Vitro Evaluation of New ABCG2 Transporter Inhibitors as Potential Anticancer Agents.
Int J Mol Sci
; 24(1)2022 Dec 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36614168
5.
Ring-Fused Cyclic Aminals from Tetrahydro-ß-carboline-Based Dipeptide Compounds.
J Org Chem
; 82(23): 12014-12027, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29091729
6.
Peptidomimetics as potent dual SARS-CoV-2 cathepsin-L and main protease inhibitors: In silico design, synthesis and pharmacological characterization.
Eur J Med Chem
; 266: 116128, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38232463
7.
In Silico Assisted Identification, Synthesis, and In Vitro Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel.
J Med Chem
; 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38782404
8.
Novel pyrrole based CB2 agonists: New insights on CB2 receptor role in regulating neurotransmitters' tone.
Eur J Med Chem
; 269: 116298, 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38493727
9.
Optimization of microwave-assisted extraction of antioxidant compounds from spring onion leaves using Box-Behnken design.
Sci Rep
; 13(1): 14923, 2023 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37691048
10.
Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis.
J Med Chem
; 66(13): 9201-9222, 2023 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37334504
11.
On the modulation of TRPM channels: Current perspectives and anticancer therapeutic implications.
Front Oncol
; 12: 1065935, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36844925
12.
The Metabolomic Profile in Amyotrophic Lateral Sclerosis Changes According to the Progression of the Disease: An Exploratory Study.
Metabolites
; 12(9)2022 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36144241
13.
New TRPM8 blockers exert anticancer activity over castration-resistant prostate cancer models.
Eur J Med Chem
; 238: 114435, 2022 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35598411
14.
Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification.
Eur J Med Chem
; 234: 114233, 2022 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35286926
15.
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity.
J Med Chem
; 65(16): 11340-11364, 2022 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35972998
16.
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization.
J Med Chem
; 65(21): 14456-14480, 2022 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36318728
17.
Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization.
Eur J Med Chem
; 226: 113863, 2021 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34571172
18.
Exploration of TRPM8 Binding Sites by ß-Carboline-Based Antagonists and Their In Vitro Characterization and In Vivo Analgesic Activities.
J Med Chem
; 63(17): 9672-9694, 2020 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32787109
19.
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators.
J Med Chem
; 63(1): 163-185, 2020 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31815462
20.
An Efficient Approach to Aromatic Aminomethylation Using Dichloromethane as Methylene Source.
Front Chem
; 7: 568, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31457005