Detalhe da pesquisa
1.
A bifunctional O-antigen polymerase structure reveals a new glycosyltransferase family.
Nat Chem Biol
; 16(4): 450-457, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152541
2.
Analysis of the Topology and Active-Site Residues of WbbF, a Putative O-Polysaccharide Synthase from Salmonella enterica Serovar Borreze.
J Bacteriol
; 202(5)2020 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31792013
3.
Klebsiella pneumoniae O1 and O2ac antigens provide prototypes for an unusual strategy for polysaccharide antigen diversification.
J Biol Chem
; 294(28): 10863-10876, 2019 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31138653
4.
Substrate recognition by a carbohydrate-binding module in the prototypical ABC transporter for lipopolysaccharide O-antigen from Escherichia coli O9a.
J Biol Chem
; 294(41): 14978-14990, 2019 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31416837
5.
Molecular basis for the structural diversity in serogroup O2-antigen polysaccharides in Klebsiella pneumoniae.
J Biol Chem
; 293(13): 4666-4679, 2018 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29602878
6.
The Klebsiella pneumoniae O12 ATP-binding Cassette (ABC) Transporter Recognizes the Terminal Residue of Its O-antigen Polysaccharide Substrate.
J Biol Chem
; 291(18): 9748-61, 2016 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26934919
7.
Lipopolysaccharide O antigen size distribution is determined by a chain extension complex of variable stoichiometry in Escherichia coli O9a.
Proc Natl Acad Sci U S A
; 111(17): 6407-12, 2014 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-24733938
8.
Domain interactions control complex formation and polymerase specificity in the biosynthesis of the Escherichia coli O9a antigen.
J Biol Chem
; 290(2): 1075-85, 2015 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25422321
9.
Structure of WbdD: a bifunctional kinase and methyltransferase that regulates the chain length of the O antigen in Escherichia coli O9a.
Mol Microbiol
; 86(3): 730-42, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22970759
10.
The lipid linked oligosaccharide polymerase Wzy and its regulating co-polymerase, Wzz, from enterobacterial common antigen biosynthesis form a complex.
Open Biol
; 13(3): 220373, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36944376
11.
Hypermucoviscosity Regulator RmpD Interacts with Wzc and Controls Capsular Polysaccharide Chain Length.
mBio
; 14(3): e0080023, 2023 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37140436
12.
Inhibiting fatty acid synthesis overcomes colistin resistance.
Nat Microbiol
; 8(6): 1026-1038, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37127701
13.
In vitro reconstruction of the chain termination reaction in biosynthesis of the Escherichia coli O9a O-polysaccharide: the chain-length regulator, WbdD, catalyzes the addition of methyl phosphate to the non-reducing terminus of the growing glycan.
J Biol Chem
; 286(48): 41391-41401, 2011 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21990359
14.
Crystallization, dehydration and experimental phasing of WbdD, a bifunctional kinase and methyltransferase from Escherichia coli O9a.
Acta Crystallogr D Biol Crystallogr
; 68(Pt 10): 1371-9, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22993091
15.
Wza the translocon for E. coli capsular polysaccharides defines a new class of membrane protein.
Nature
; 444(7116): 226-9, 2006 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-17086202
16.
The molecular basis of regulation of bacterial capsule assembly by Wzc.
Nat Commun
; 12(1): 4349, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34272394
17.
Coordination of polymerization, chain termination, and export in assembly of the Escherichia coli lipopolysaccharide O9a antigen in an ATP-binding cassette transporter-dependent pathway.
J Biol Chem
; 284(44): 30662-72, 2009 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-19734145
18.
Structure-function relationships of the outer membrane translocon Wza investigated by cryo-electron microscopy and mutagenesis.
J Struct Biol
; 166(2): 172-82, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19236919
19.
A coiled-coil domain acts as a molecular ruler to regulate O-antigen chain length in lipopolysaccharide.
Nat Struct Mol Biol
; 22(1): 50-56, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25504321
20.
The 3D structure of a periplasm-spanning platform required for assembly of group 1 capsular polysaccharides in Escherichia coli.
Proc Natl Acad Sci U S A
; 104(7): 2390-5, 2007 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-17283336