Detalhe da pesquisa
1.
A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria.
Cell
; 165(6): 1493-1506, 2016 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27238023
2.
Systematically testing human HMBS missense variants to reveal mechanism and pathogenic variation.
Am J Hum Genet
; 110(10): 1769-1786, 2023 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37729906
3.
Spectrum of splicing variants in disease genes and the ability of RNA analysis to reduce uncertainty in clinical interpretation.
Am J Hum Genet
; 108(4): 696-708, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33743207
4.
Applications of artificial intelligence in clinical laboratory genomics.
Am J Med Genet C Semin Med Genet
; 193(3): e32057, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37507620
5.
Conservation of conformational dynamics across prokaryotic actins.
PLoS Comput Biol
; 15(4): e1006683, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30951524
6.
Rapid, precise quantification of bacterial cellular dimensions across a genomic-scale knockout library.
BMC Biol
; 15(1): 17, 2017 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28222723
7.
Effects of polymerization and nucleotide identity on the conformational dynamics of the bacterial actin homolog MreB.
Proc Natl Acad Sci U S A
; 111(9): 3585-90, 2014 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24550504
8.
Rod-like bacterial shape is maintained by feedback between cell curvature and cytoskeletal localization.
Proc Natl Acad Sci U S A
; 111(11): E1025-34, 2014 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24550515
9.
Systematically testing human HMBS missense variants to reveal mechanism and pathogenic variation.
bioRxiv
; 2023 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36798224
10.
Extracting phylogenetic dimensions of coevolution reveals hidden functional signals.
Sci Rep
; 12(1): 820, 2022 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35039514
11.
RodZ modulates geometric localization of the bacterial actin MreB to regulate cell shape.
Nat Commun
; 9(1): 1280, 2018 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29599448
12.
Coupling between Protein Stability and Catalytic Activity Determines Pathogenicity of G6PD Variants.
Cell Rep
; 18(11): 2592-2599, 2017 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28297664
13.
Strain Library Imaging Protocol for high-throughput, automated single-cell microscopy of large bacterial collections arrayed on multiwell plates.
Nat Protoc
; 12(2): 429-438, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28125106
14.
Deep Phenotypic Mapping of Bacterial Cytoskeletal Mutants Reveals Physiological Robustness to Cell Size.
Curr Biol
; 27(22): 3419-3429.e4, 2017 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29103935
15.
Coordination of peptidoglycan synthesis and outer membrane constriction during Escherichia coli cell division.
Elife
; 42015 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25951518
16.
Systematic perturbation of cytoskeletal function reveals a linear scaling relationship between cell geometry and fitness.
Cell Rep
; 9(4): 1528-37, 2014 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25456141