Detalhe da pesquisa
1.
Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.
Cell
; 184(10): 2696-2714.e25, 2021 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33891876
2.
Preclinical Evaluation of the Reversible Monoacylglycerol Lipase PET Tracer (R)-[11C]YH132: Application in Drug Development and Neurodegenerative Diseases.
Chembiochem
; 25(7): e202300819, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38441502
3.
Intracellular transport and regulation of transcytosis across the blood-brain barrier.
Cell Mol Life Sci
; 76(6): 1081-1092, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30523362
4.
Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease.
Brain
; 137(Pt 10): 2834-46, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25085375
5.
Pharmacological blockade of 2-AG degradation ameliorates clinical, neuroinflammatory and synaptic alterations in experimental autoimmune encephalomyelitis.
Neuropharmacology
; 252: 109940, 2024 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38570068
6.
Identification of (R)-[18F]YH134 for Monoacylglycerol Lipase Neuroimaging and Exploration of Its Use for Central Nervous System and Peripheral Drug Development.
J Nucl Med
; 65(2): 300-305, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38164615
7.
A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence.
Nat Commun
; 14(1): 8039, 2023 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38052772
8.
A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature.
PLoS One
; 17(9): e0268590, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36084029
9.
Development of High Brain-Penetrant and Reversible Monoacylglycerol Lipase PET Tracers for Neuroimaging.
J Med Chem
; 65(3): 2191-2207, 2022 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35089028
10.
Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold.
Nucl Med Biol
; 108-109: 24-32, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35248850
11.
Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain.
Eur J Med Chem
; 243: 114750, 2022 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36137365
12.
The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells.
Nat Neurosci
; 24(11): 1522-1533, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34675436
13.
[Passive Tau immunotherapy for prevention of Tau pathology progression]. / Prévenir la progression de la pathologie Tau par immunothérapie passive.
Med Sci (Paris)
; 31(2): 132-4, 2015 Feb.
Artigo
em Francês
| MEDLINE | ID: mdl-25744257
14.
muscat detects subpopulation-specific state transitions from multi-sample multi-condition single-cell transcriptomics data.
Nat Commun
; 11(1): 6077, 2020 11 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33257685
15.
APC nuclear membrane association and microtubule polarity.
Biol Cell
; 100(4): 243-52, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18042042
16.
[Opening the brain to new therapies]. / Ouvrir le cerveau à de nouvelles thérapies.
Med Sci (Paris)
; 30(5): 486-8, 2014 May.
Artigo
em Francês
| MEDLINE | ID: mdl-24939528
17.
High-resolution Confocal Imaging of the Blood-brain Barrier: Imaging, 3D Reconstruction, and Quantification of Transcytosis.
J Vis Exp
; (129)2017 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29286366
18.
Sorting Tubules Regulate Blood-Brain Barrier Transcytosis.
Cell Rep
; 21(11): 3256-3270, 2017 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29241551
19.
Region-specific permeability of the blood-brain barrier upon pericyte loss.
J Cereb Blood Flow Metab
; 37(12): 3683-3694, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28273726
20.
Nucleofection of primary neurons.
Methods Enzymol
; 406: 374-88, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16472671