Detalhe da pesquisa
1.
Precision medicine in 2030-seven ways to transform healthcare.
Cell
; 184(6): 1415-1419, 2021 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33740447
2.
Affirming NIH's commitment to addressing structural racism in the biomedical research enterprise.
Cell
; 184(12): 3075-3079, 2021 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34115967
3.
In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice.
Nature
; 589(7843): 608-614, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33408413
4.
Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis.
Proc Natl Acad Sci U S A
; 120(7): e2206797120, 2023 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36757889
5.
Modeling islet enhancers using deep learning identifies candidate causal variants at loci associated with T2D and glycemic traits.
Proc Natl Acad Sci U S A
; 120(35): e2206612120, 2023 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37603758
6.
Subcutaneous adipose tissue splice quantitative trait loci reveal differences in isoform usage associated with cardiometabolic traits.
Am J Hum Genet
; 109(1): 66-80, 2022 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34995504
7.
Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk.
Am J Hum Genet
; 109(10): 1727-1741, 2022 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36055244
8.
Genetic effects on liver chromatin accessibility identify disease regulatory variants.
Am J Hum Genet
; 108(7): 1169-1189, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34038741
9.
Update on and Future Directions for Use of Anti-SARS-CoV-2 Antibodies: National Institutes of Health Summit on Treatment and Prevention of COVID-19.
Ann Intern Med
; 175(1): 119-126, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34724404
10.
Evaluation of musculoskeletal phenotype of the G608G progeria mouse model with lonafarnib, pravastatin, and zoledronic acid as treatment groups.
Proc Natl Acad Sci U S A
; 117(22): 12029-12040, 2020 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32404427
11.
Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences.
PLoS Genet
; 16(9): e1009019, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32915782
12.
Adipose Tissue Gene Expression Associations Reveal Hundreds of Candidate Genes for Cardiometabolic Traits.
Am J Hum Genet
; 105(4): 773-787, 2019 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31564431
13.
ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition-implications for COVID-19.
Int J Obes (Lond)
; 46(8): 1478-1486, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35589964
14.
Base editor treats progeria in mice.
Nature
; 2021 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34285403
15.
Transient induction of telomerase expression mediates senescence and reduces tumorigenesis in primary fibroblasts.
Proc Natl Acad Sci U S A
; 116(38): 18983-18993, 2019 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31481614
16.
Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle.
Proc Natl Acad Sci U S A
; 116(22): 10883-10888, 2019 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31076557
17.
Report of the National Institutes of Health SARS-CoV-2 Antiviral Therapeutics Summit.
J Infect Dis
; 224(Supplement_1): S1-S21, 2021 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34111271
18.
Colocalization of GWAS and eQTL signals at loci with multiple signals identifies additional candidate genes for body fat distribution.
Hum Mol Genet
; 28(24): 4161-4172, 2019 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31691812
19.
TUBB3 Arg262His causes a recognizable syndrome including CFEOM3, facial palsy, joint contractures, and early-onset peripheral neuropathy.
Hum Genet
; 140(12): 1709-1731, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34652576
20.
A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression.
Am J Hum Genet
; 102(4): 620-635, 2018 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29625024