Detalhe da pesquisa
1.
Pharmacokinetics and safety of LEAD-452, an EGFR-specific 4-1BB-agonistic trimerbody in non-human primates.
Toxicol Appl Pharmacol
; 487: 116961, 2024 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38740095
2.
T Cell-Redirecting Strategies to 'STAb' Tumors: Beyond CARs and Bispecific Antibodies.
Trends Immunol
; 40(3): 243-257, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30827461
3.
Immuno-PET Imaging and Pharmacokinetics of an Anti-CEA scFv-based Trimerbody and Its Monomeric Counterpart in Human Gastric Carcinoma-Bearing Mice.
Mol Pharm
; 16(3): 1025-1035, 2019 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30726099
4.
Bispecific light T-cell engagers for gene-based immunotherapy of epidermal growth factor receptor (EGFR)-positive malignancies.
Cancer Immunol Immunother
; 67(8): 1251-1260, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29869168
5.
Role of nucleotide-binding oligomerization domain 1 (NOD1) in pericyte-mediated vascular inflammation.
J Cell Mol Med
; 20(5): 980-6, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26915562
6.
Proteasome activator complex PA28 identified as an accessible target in prostate cancer by in vivo selection of human antibodies.
Proc Natl Acad Sci U S A
; 110(34): 13791-6, 2013 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23918357
7.
Lipopolysaccharide activates Toll-like receptor 4 (TLR4)-mediated NF-κB signaling pathway and proinflammatory response in human pericytes.
J Biol Chem
; 289(4): 2457-68, 2014 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24307174
8.
Efficient production of single-chain fragment variable-based N-terminal trimerbodies in Pichia pastoris.
Microb Cell Fact
; 13: 116, 2014 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25112455
9.
The efficacy versus toxicity profile of combination virotherapy and TLR immunotherapy highlights the danger of administering TLR agonists to oncolytic virus-treated mice.
Mol Ther
; 21(2): 348-57, 2013 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23011032
10.
Combination of T cell-redirecting strategies with a bispecific antibody blocking TGF-ß and PD-L1 enhances antitumor responses.
Oncoimmunology
; 13(1): 2338558, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38623463
11.
When three is not a crowd: trispecific antibodies for enhanced cancer immunotherapy.
Theranostics
; 13(3): 1028-1041, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36793863
12.
A PD-L1/EGFR bispecific antibody combines immune checkpoint blockade and direct anti-cancer action for an enhanced anti-tumor response.
Oncoimmunology
; 12(1): 2205336, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37114242
13.
Dendritic Cell-Mediated Cross-Priming by a Bispecific Neutralizing Antibody Boosts Cytotoxic T Cell Responses and Protects Mice against SARS-CoV-2.
Adv Sci (Weinh)
; 10(34): e2304818, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37863812
14.
Applications of trimerbodies in cancer immunotherapy.
Int Rev Cell Mol Biol
; 369: 71-87, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35777865
15.
Trispecific T-cell engagers for dual tumor-targeting of colorectal cancer.
Oncoimmunology
; 11(1): 2034355, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35154908
16.
Tumor targeted 4-1BB agonist antibody-albumin fusions with high affinity to FcRn induce anti-tumor immunity without toxicity.
iScience
; 25(9): 104958, 2022 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36072551
17.
Overcoming CAR-Mediated CD19 Downmodulation and Leukemia Relapse with T Lymphocytes Secreting Anti-CD19 T-cell Engagers.
Cancer Immunol Res
; 10(4): 498-511, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35362043
18.
In vivo secretion of anti-CD3 × anti-tumor bispecific antibodies by gene-modified cells: over a decade of T-cell engagement.
Mol Ther
; 23(4): 612-3, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25849422
19.
An Fc-free EGFR-specific 4-1BB-agonistic Trimerbody Displays Broad Antitumor Activity in Humanized Murine Cancer Models without Toxicity.
Clin Cancer Res
; 27(11): 3167-3177, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33785484
20.
Tumor immunotherapy using gene-modified human mesenchymal stem cells loaded into synthetic extracellular matrix scaffolds.
Stem Cells
; 27(3): 753-60, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19096041