Detalhe da pesquisa
1.
Crystal Structure and Activity Studies of the C11 Cysteine Peptidase from Parabacteroides merdae in the Human Gut Microbiome.
J Biol Chem
; 291(18): 9482-91, 2016 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26940874
2.
PNT1 Is a C11 Cysteine Peptidase Essential for Replication of the Trypanosome Kinetoplast.
J Biol Chem
; 291(18): 9492-500, 2016 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26940875
3.
Phosphoenolpyruvate carboxylase identified as a key enzyme in erythrocytic Plasmodium falciparum carbon metabolism.
PLoS Pathog
; 10(1): e1003876, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24453970
4.
Leishmania TDR1 structure, a unique trimeric glutathione transferase capable of deglutathionylation and antimonial prodrug activation.
Proc Natl Acad Sci U S A
; 109(29): 11693-8, 2012 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22753509
5.
Crystal structure of a Trypanosoma brucei metacaspase.
Proc Natl Acad Sci U S A
; 109(19): 7469-74, 2012 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22529389
6.
Distinct roles in autophagy and importance in infectivity of the two ATG4 cysteine peptidases of Leishmania major.
J Biol Chem
; 288(5): 3678-90, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23166325
7.
Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance.
Genome Res
; 21(12): 2143-56, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22038251
8.
ATG5 is essential for ATG8-dependent autophagy and mitochondrial homeostasis in Leishmania major.
PLoS Pathog
; 8(5): e1002695, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22615560
9.
Ecotin-like serine peptidase inhibitor ISP1 of Leishmania major plays a role in flagellar pocket dynamics and promastigote differentiation.
Cell Microbiol
; 14(8): 1271-86, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22486816
10.
Trypanosoma brucei metacaspase 4 is a pseudopeptidase and a virulence factor.
J Biol Chem
; 286(46): 39914-25, 2011 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21949125
11.
Identification of lead compounds targeting the cathepsin B-like enzyme of Eimeria tenella.
Antimicrob Agents Chemother
; 56(3): 1190-201, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22143531
12.
Structure of Leishmania major cysteine synthase.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 68(Pt 7): 738-43, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22750854
13.
Morphological events during the cell cycle of Leishmania major.
Eukaryot Cell
; 10(11): 1429-38, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21926331
14.
Mechanistic studies on the enzymatic processing of fluorinated methionine analogues by Trichomonas vaginalis methionine γ-lyase.
Biochem J
; 438(3): 513-21, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21658005
15.
Plasmodium falciparum LipB mutants display altered redox and carbon metabolism in asexual stages and cannot complete sporogony in Anopheles mosquitoes.
Int J Parasitol
; 51(6): 441-453, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33713652
16.
The mercaptopyruvate sulfurtransferase of Trichomonas vaginalis links cysteine catabolism to the production of thioredoxin persulfide.
J Biol Chem
; 284(48): 33485-94, 2009 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19762467
17.
Influence of parasite encoded inhibitors of serine peptidases in early infection of macrophages with Leishmania major.
Cell Microbiol
; 11(1): 106-20, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19016791
18.
Profiling of lipids in Leishmania donovani using hydrophilic interaction chromatography in combination with Fourier transform mass spectrometry.
Rapid Commun Mass Spectrom
; 24(14): 2074-82, 2010 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20552712
19.
Design and evaluation of Trypanosoma brucei metacaspase inhibitors.
Bioorg Med Chem Lett
; 20(6): 2001-6, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20167486
20.
Towards an unbiased metabolic profiling of protozoan parasites: optimisation of a Leishmania sampling protocol for HILIC-orbitrap analysis.
Anal Bioanal Chem
; 398(5): 2059-69, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20824428