Detalhe da pesquisa
1.
A Genetic Map of the Response to DNA Damage in Human Cells.
Cell
; 182(2): 481-496.e21, 2020 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32649862
2.
Genome-wide prediction of topoisomerase IIß binding by architectural factors and chromatin accessibility.
PLoS Comput Biol
; 17(1): e1007814, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33465072
3.
Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2.
Nucleic Acids Res
; 48(11): 6310-6325, 2020 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32356875
4.
TDP2 suppresses genomic instability induced by androgens in the epithelial cells of prostate glands.
Genes Cells
; 25(7): 450-465, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32277721
5.
The insecticides permethrin and chlorpyrifos show limited genotoxicity and no leukemogenic potential in human and murine hematopoietic stem progenitor cells.
Haematologica
; 107(2): 544-549, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34706497
6.
TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo.
PLoS Genet
; 9(3): e1003226, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23505375
7.
A human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage.
Nature
; 461(7264): 674-8, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19794497
8.
Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination.
Nucleic Acids Res
; 41(3): 1669-83, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23254329
9.
CDK targets Sae2 to control DNA-end resection and homologous recombination.
Nature
; 455(7213): 689-92, 2008 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-18716619
10.
TDP2 is a regulator of estrogen-responsive oncogene expression.
NAR Cancer
; 6(2): zcae016, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38596431
11.
Topological regulation of the estrogen transcriptional response by ZATT-mediated inhibition of TOP2B activity.
bioRxiv
; 2024 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38328138
12.
Smc5-Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination.
Nat Cell Biol
; 8(9): 1032-4, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16892052
13.
TDP2/TTRAP is the major 5'-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damage.
J Biol Chem
; 286(1): 403-9, 2011 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21030584
14.
Data of transcriptional effects of the merbarone-mediated inhibition of TOP2.
Data Brief
; 44: 108499, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35983130
15.
Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing.
Cell Rep
; 35(2): 108977, 2021 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33852840
16.
The Dot1 histone methyltransferase and the Rad9 checkpoint adaptor contribute to cohesin-dependent double-strand break repair by sister chromatid recombination in Saccharomyces cerevisiae.
Genetics
; 182(2): 437-46, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19332880
17.
Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency.
Nat Commun
; 11(1): 910, 2020 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32060399
18.
Different genetic requirements for repair of replication-born double-strand breaks by sister-chromatid recombination and break-induced replication.
Nucleic Acids Res
; 35(19): 6560-70, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17905819
19.
"An End to a Means": How DNA-End Structure Shapes the Double-Strand Break Repair Process.
Front Mol Biosci
; 6: 153, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31998749
20.
GSE4 peptide suppresses oxidative and telomere deficiencies in ataxia telangiectasia patient cells.
Cell Death Differ
; 26(10): 1998-2014, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30670828