Detalhe da pesquisa
1.
A glycolytic metabolite bypasses "two-hit" tumor suppression by BRCA2.
Cell
; 187(9): 2269-2287.e16, 2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38608703
2.
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.
Cell
; 167(2): 457-470.e13, 2016 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27667687
3.
Fumarate induces vesicular release of mtDNA to drive innate immunity.
Nature
; 615(7952): 499-506, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36890229
4.
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production.
Nature
; 615(7952): 490-498, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36890227
5.
Mitochondria-Endoplasmic Reticulum Contact Sites Function as Immunometabolic Hubs that Orchestrate the Rapid Recall Response of Memory CD8+ T Cells.
Immunity
; 48(3): 542-555.e6, 2018 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29523440
6.
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Nature
; 556(7699): 113-117, 2018 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29590092
7.
Signaling metabolite L-2-hydroxyglutarate activates the transcription factor HIF-1α in lipopolysaccharide-activated macrophages.
J Biol Chem
; 298(2): 101501, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34929172
8.
Oral famotidine versus placebo in non-hospitalised patients with COVID-19: a randomised, double-blind, data-intense, phase 2 clinical trial.
Gut
; 71(5): 879-888, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35144974
9.
BCAT1 affects mitochondrial metabolism independently of leucine transamination in activated human macrophages.
J Cell Sci
; 133(22)2020 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33148611
10.
Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses.
Mol Syst Biol
; 17(1): e9730, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33502086
11.
Glutaminolysis is a metabolic dependency in FLT3ITD acute myeloid leukemia unmasked by FLT3 tyrosine kinase inhibition.
Blood
; 131(15): 1639-1653, 2018 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29463564
12.
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
Nature
; 515(7527): 431-435, 2014 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25383517
13.
Corrigendum to "Post-translational regulation of metabolism in fumarate hydratase deficient cancer cells" [Metabol. Eng. 45 (2018) 149-157].
Metab Eng
; 82: 297-298, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38245482
14.
Extracellular vesicles are independent metabolic units with asparaginase activity.
Nat Chem Biol
; 13(9): 951-955, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28671681
15.
Ischemic preconditioning protects against cardiac ischemia reperfusion injury without affecting succinate accumulation or oxidation.
J Mol Cell Cardiol
; 123: 88-91, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30118790
16.
Post-translational regulation of metabolism in fumarate hydratase deficient cancer cells.
Metab Eng
; 45: 149-157, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29191787
17.
Differential effects of reduced protein diets on fatty acid composition and gene expression in muscle and subcutaneous adipose tissue of Alentejana purebred and Large White × Landrace × Pietrain crossbred pigs.
Br J Nutr
; 110(2): 216-29, 2013 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23286604
18.
Rapid fractionation of mitochondria from mouse liver and heart reveals in vivo metabolite compartmentation.
FEBS Lett
; 597(2): 246-261, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36217875
19.
Energy substrate metabolism, mitochondrial structure and oxidative stress after cardiac ischemia-reperfusion in mice lacking UCP3.
Free Radic Biol Med
; 205: 244-261, 2023 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37295539
20.
Effect of slaughter season and muscle type on the fatty acid composition, including conjugated linoleic acid isomers, and nutritional value of intramuscular fat in organic beef.
J Sci Food Agric
; 92(12): 2428-35, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22473659