Detalhe da pesquisa
1.
Tumor cellular proteasome inhibition and growth suppression by 8-hydroxyquinoline and clioquinol requires their capabilities to bind copper and transport copper into cells.
J Biol Inorg Chem
; 15(2): 259-69, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19809836
2.
Proteasome inhibition in human breast cancer cells with high catechol-O-methyltransferase activity by green tea polyphenol EGCG analogs.
Bioorg Med Chem
; 18(3): 1252-8, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20045338
3.
Shikonin exerts antitumor activity via proteasome inhibition and cell death induction in vitro and in vivo.
Int J Cancer
; 124(10): 2450-9, 2009 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19165859
4.
New difluoro Knoevenagel condensates of curcumin, their Schiff bases and copper complexes as proteasome inhibitors and apoptosis inducers in cancer cells.
Pharm Res
; 26(8): 1874-80, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19421843
5.
Comparative activities of nickel(II) and zinc(II) complexes of asymmetric [NN'O] ligands as 26S proteasome inhibitors.
Inorg Chem
; 48(13): 5928-37, 2009 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19496541
6.
Inhibition of the proteasome activity by gallium(III) complexes contributes to their anti prostate tumor effects.
Cancer Res
; 67(19): 9258-65, 2007 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17909033
7.
Clioquinol, a therapeutic agent for Alzheimer's disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, and antitumor activities in human prostate cancer cells and xenografts.
Cancer Res
; 67(4): 1636-44, 2007 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17308104
8.
Anti-tumor activity of N-thiolated beta-lactam antibiotics.
Cancer Lett
; 268(1): 63-9, 2008 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-18468785
9.
Prodrugs of fluoro-substituted benzoates of EGC as tumor cellular proteasome inhibitors and apoptosis inducers.
Int J Mol Sci
; 9(6): 951-961, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19325839
10.
Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity.
Cancer Res
; 66(21): 10425-33, 2006 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17079463
11.
Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice.
Cancer Res
; 66(9): 4758-65, 2006 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16651429
12.
Structure-proteasome-inhibitory activity relationships of dietary flavonoids in human cancer cells.
Front Biosci
; 12: 1935-45, 2007 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17127432
13.
Sodium diethyldithiocarbamate, an AIDS progression inhibitor and a copper-binding compound, has proteasome-inhibitory and apoptosis-inducing activities in cancer cells.
Int J Mol Med
; 19(5): 809-16, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17390087
14.
Evaluation of copper-dependent proteasome-inhibitory and apoptosis-inducing activities of novel pyrrolidine dithiocarbamate analogues.
Int J Mol Med
; 20(6): 919-25, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17982703
15.
Apoptotic-inducing activity of novel polycyclic aromatic compounds in human leukemic cells.
Int J Mol Med
; 17(5): 931-5, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16596283
16.
Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells.
Breast Cancer Res
; 7(6): R897-908, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16280039
17.
Inhibition of prostate cancer cellular proteasome activity by a pyrrolidine dithiocarbamate-copper complex is associated with suppression of proliferation and induction of apoptosis.
Front Biosci
; 10: 2932-9, 2005 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15970547
18.
Inhibition of tumor cellular proteasome activity by triptolide extracted from the Chinese medicinal plant 'thunder god vine'.
Anticancer Res
; 31(1): 1-10, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21273574
19.
Disulfiram treatment facilitates phosphoinositide 3-kinase inhibition in human breast cancer cells in vitro and in vivo.
Cancer Res
; 70(10): 3996-4004, 2010 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20424113
20.
Evaluation of curcumin acetates and amino acid conjugates as proteasome inhibitors.
Int J Mol Med
; 26(4): 447-55, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20818481