Detalhe da pesquisa
1.
Mechanisms of Nitrosamine Mutagenicity and Their Relationship to Rodent Carcinogenic Potency.
Chem Res Toxicol
; 37(2): 181-198, 2024 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38316048
2.
Acceptable intakes (AIs) for 11 small molecule N-nitrosamines (NAs).
Regul Toxicol Pharmacol
; 142: 105415, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37257751
3.
Predicting DNA-Reactivity of N-Nitrosamines: A Quantum Chemical Approach.
Chem Res Toxicol
; 35(11): 2068-2084, 2022 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36302168
4.
A weight of evidence review of the genotoxicity of titanium dioxide (TiO2).
Regul Toxicol Pharmacol
; 136: 105263, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36228836
5.
Use of the bacterial reverse mutation assay to predict carcinogenicity of N-nitrosamines.
Regul Toxicol Pharmacol
; 135: 105247, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35998738
6.
Use of less-than-lifetime (LTL) durational limits for nitrosamines: Case study of N-Nitrosodiethylamine (NDEA).
Regul Toxicol Pharmacol
; 123: 104926, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-33862169
7.
Computational Investigation of Drug Phototoxicity: Photosafety Assessment, Photo-Toxophore Identification, and Machine Learning.
Chem Res Toxicol
; 32(11): 2338-2352, 2019 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31625387
8.
A critical appraisal of the sensitivity of in vivo genotoxicity assays in detecting human carcinogens.
Mutagenesis
; 33(2): 179-193, 2018 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29669112
9.
Computational Models for Human and Animal Hepatotoxicity with a Global Application Scope.
Chem Res Toxicol
; 29(5): 757-67, 2016 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26914516
10.
Assessment of the performance of the Ames MPF™ assay: A multicenter collaborative study with six coded chemicals.
Mutat Res Genet Toxicol Environ Mutagen
; 893: 503718, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38272629
11.
The evolving role of investigative toxicology in the pharmaceutical industry.
Nat Rev Drug Discov
; 22(4): 317-335, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36781957
12.
Improvement of in vivo genotoxicity assessment: combination of acute tests and integration into standard toxicity testing.
Mutat Res
; 723(2): 108-20, 2011 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21182982
13.
Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies.
Mutat Res
; 702(1): 40-69, 2010 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20656055
14.
Optimizing drug discovery by Investigative Toxicology: Current and future trends.
ALTEX
; 36(2): 289-313, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30570669
15.
Cytotoxicity evaluation using cryopreserved primary human hepatocytes in various culture formats.
Toxicol Lett
; 258: 207-215, 2016 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27363785
16.
Photochemical genotoxicity: principles and test methods. Report of a GUM task force.
Mutat Res
; 566(1): 65-91, 2004 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-14706512
17.
Predictive in silico off-target profiling in drug discovery.
Future Med Chem
; 6(3): 295-317, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24575966
18.
Follow-up actions from positive results of in vitro genetic toxicity testing.
Environ Mol Mutagen
; 52(3): 177-204, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20963811