Detalhe da pesquisa
1.
The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis.
Nat Rev Cancer
; 6(12): 947-60, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17128211
2.
Fatal Epileptic Seizures in Mice Having Compromised Glutathione and Ascorbic Acid Biosynthesis.
Antioxidants (Basel)
; 12(2)2023 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36830006
3.
Redox dysregulation affects the ventral but not dorsal hippocampus: impairment of parvalbumin neurons, gamma oscillations, and related behaviors.
J Neurosci
; 30(7): 2547-58, 2010 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20164340
4.
Generation of a Slc39a8 hypomorph mouse: markedly decreased ZIP8 Zn²âº/(HCO3â»)2 transporter expression.
Biochem Biophys Res Commun
; 410(2): 289-94, 2011 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21658371
5.
Oral N-acetylcysteine rescues lethality of hepatocyte-specific Gclc-knockout mice, providing a model for hepatic cirrhosis.
J Hepatol
; 53(6): 1085-94, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20810184
6.
Glutathione deficient C57BL/6J mice are not sensitized to ozone-induced lung injury.
Biochem Biophys Res Commun
; 396(2): 407-12, 2010 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20417186
7.
Knock-in mouse lines expressing either mitochondrial or microsomal CYP1A1: differing responses to dietary benzo[a]pyrene as proof of principle.
Mol Pharmacol
; 75(3): 555-67, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19047483
8.
Curcumin, quercetin, and tBHQ modulate glutathione levels in astrocytes and neurons: importance of the glutamate cysteine ligase modifier subunit.
J Neurochem
; 108(6): 1410-22, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19183254
9.
Slc39a14 gene encodes ZIP14, a metal/bicarbonate symporter: similarities to the ZIP8 transporter.
Mol Pharmacol
; 73(5): 1413-23, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18270315
10.
Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract.
Free Radic Biol Med
; 44(4): 570-83, 2008 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17997381
11.
Cd2+ versus Zn2+ uptake by the ZIP8 HCO3--dependent symporter: kinetics, electrogenicity and trafficking.
Biochem Biophys Res Commun
; 365(4): 814-20, 2008 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-18037372
12.
Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway.
Hepatology
; 46(5): 1597-610, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17668877
13.
Interaction between the catalytic and modifier subunits of glutamate-cysteine ligase.
Biochem Pharmacol
; 74(2): 372-81, 2007 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17517378
14.
Genetic differences in lethality of newborn mice treated in utero with coplanar versus non-coplanar hexabromobiphenyl.
Toxicol Sci
; 89(2): 454-64, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16291824
15.
Toward the evaluation of function in genetic variability: characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2 locus.
Hum Mutat
; 25(2): 196-206, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15643613
16.
Butylhydroquinone protects cells genetically deficient in glutathione biosynthesis from arsenite-induced apoptosis without significantly changing their prooxidant status.
Toxicol Sci
; 87(2): 365-84, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16014739
17.
Genetically altered mice to evaluate glutathione homeostasis in health and disease.
Free Radic Biol Med
; 37(10): 1511-26, 2004 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15477003
18.
Pharmacological rescue of the 14CoS/14CoS mouse: hepatocyte apoptosis is likely caused by endogenous oxidative stress.
Free Radic Biol Med
; 35(4): 351-67, 2003 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12899938
19.
Mitochondrial reactive oxygen production is dependent on the aromatic hydrocarbon receptor.
Free Radic Biol Med
; 33(9): 1268-78, 2002 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12398935
20.
Cyp1a2 protects against reactive oxygen production in mouse liver microsomes.
Free Radic Biol Med
; 36(5): 605-17, 2004 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14980704