Detalhe da pesquisa
1.
New oral protease-activated receptor 4 antagonist BMS-986120: tolerability, pharmacokinetics, pharmacodynamics, and gene variant effects in humans.
Platelets
; 33(7): 969-978, 2022 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35758258
2.
First-in-human study to assess the safety, pharmacokinetics and pharmacodynamics of BMS-962212, a direct, reversible, small molecule factor XIa inhibitor in non-Japanese and Japanese healthy subjects.
Br J Clin Pharmacol
; 84(5): 876-887, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29346838
3.
First-in-human study of milvexian, an oral, direct, small molecule factor XIa inhibitor.
Clin Transl Sci
; 15(2): 330-342, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34558200
4.
Effects of Itraconazole and Diltiazem on the Pharmacokinetics and Pharmacodynamics of Milvexian, A Factor XIa Inhibitor.
Cardiol Ther
; 11(3): 407-419, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35641780
5.
Safety, pharmacokinetics, and pharmacodynamics of milvexian in healthy Japanese participants.
Sci Rep
; 12(1): 5165, 2022 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35338177
6.
Effects of rifampin on the pharmacokinetics and pharmacodynamics of milvexian, a potent, selective, oral small molecule factor XIa inhibitor.
Sci Rep
; 12(1): 22239, 2022 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36564395
7.
Disease Management and Outcomes in Patients Hospitalized for Acute Heart Failure in Japan.
Cardiol Ther
; 10(1): 211-228, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33609268
8.
Haemodynamic effects of the nitroxyl donor cimlanod (BMS-986231) in chronic heart failure: a randomized trial.
Eur J Heart Fail
; 23(7): 1147-1155, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33620131
9.
Effects of a Novel Nitroxyl Donor in Acute Heart Failure: The STAND-UP AHF Study.
JACC Heart Fail
; 9(2): 146-157, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33248986
10.
In-Hospital Therapy for Heart Failure With Reduced Ejection Fraction in the United States.
JACC Heart Fail
; 8(11): 943-953, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32800512
11.
Rationale and design for the development of a novel nitroxyl donor in patients with acute heart failure.
Eur J Heart Fail
; 21(8): 1022-1031, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31168885
12.
Reassessing Phase II Heart Failure Clinical Trials: Consensus Recommendations.
Circ Heart Fail
; 10(4)2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28356300
13.
Patients Hospitalized for De Novo Versus Worsening Chronic Heart Failure in the United States.
J Am Coll Cardiol
; 77(7): 1023-1025, 2021 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33602461
14.
Identification and characterization of 1,25D3-membrane-associated rapid response, steroid (1,25D3-MARRS) binding protein.
J Steroid Biochem Mol Biol
; 89-90(1-5): 281-5, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15225786
15.
A gene expression signature that classifies human atherosclerotic plaque by relative inflammation status.
Circ Cardiovasc Genet
; 4(6): 595-604, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22010137
16.
Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop.
J Biol Chem
; 278(19): 17036-43, 2003 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-12624114