Detalhe da pesquisa
1.
Design optimisation for pharmacokinetic modeling of a cocktail of phenotyping drugs.
Pharm Stat
; 15(2): 165-77, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26689604
2.
Metabolic detoxification pathways for 5-methoxy-sterigmatocystin in primary tracheal epithelial cells.
Xenobiotica
; 44(1): 1-9, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23756242
3.
New untargeted metabolic profiling combining mass spectrometry and isotopic labeling: application on Aspergillus fumigatus grown on wheat.
Anal Chem
; 85(17): 8412-20, 2013 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23901908
4.
Acebutolol and alprenolol metabolism predictions: comparative study of electrochemical and cytochrome P450-catalyzed reactions using liquid chromatography coupled to high-resolution mass spectrometry.
Anal Bioanal Chem
; 405(18): 6077-85, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23700103
5.
Can a cocktail designed for phenotyping pharmacokinetics and metabolism enzymes in human be used efficiently in rat?
Xenobiotica
; 42(4): 349-54, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22321050
6.
In vivo effects of zearalenone on the expression of proteins involved in the detoxification of rat xenobiotics.
Environ Toxicol
; 27(2): 98-108, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20607812
7.
Jewelry boxes contaminated by Aspergillus oryzae: an occupational health risk?
J Occup Environ Hyg
; 9(7): 460-6, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22702230
8.
Contribution of uniformly 13C-enriched sterigmatocystin to the study of its pulmonary metabolism.
Rapid Commun Mass Spectrom
; 25(19): 2704-10, 2011 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21913247
9.
Metabolic detoxication pathways for sterigmatocystin in primary tracheal epithelial cells.
Chem Res Toxicol
; 23(11): 1673-81, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20929267
10.
Biochemical and analytical development of the CIME cocktail for drug fate assessment in humans.
Rapid Commun Mass Spectrom
; 24(16): 2407-19, 2010 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20658680
11.
In vitro cytochrome p450 formation of a mono-hydroxylated metabolite of zearalenone exhibiting estrogenic activities: possible occurrence of this metabolite in vivo.
Int J Mol Sci
; 10(4): 1824-37, 2009 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-19468341
12.
Improvement of cyclophosphamide activation by CYP2B6 mutants: from in silico to ex vivo.
Mol Pharmacol
; 73(4): 1122-33, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18212249
13.
Isolation and cytotoxicity of low-molecular-weight metabolites of Candida albicans.
Front Biosci
; 13: 6893-904, 2008 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18508703
14.
Metabolism of phenylahistin enantiomers by cytochromes P450: a possible explanation for their different cytotoxicity.
Drug Metab Dispos
; 36(11): 2381-92, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18687804
15.
Verruculogen associated with Aspergillus fumigatus hyphae and conidia modifies the electrophysiological properties of human nasal epithelial cells.
BMC Microbiol
; 7: 5, 2007 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-17244350
16.
The inability of Byssochlamys fulva to produce patulin is related to absence of 6-methylsalicylic acid synthase and isoepoxydon dehydrogenase genes.
Int J Food Microbiol
; 115(2): 131-9, 2007 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-17169453
17.
Evidencing 98 secondary metabolites of Penicillium verrucosum using substrate isotopic labeling and high-resolution mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1071: 29-43, 2017 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28351740
18.
Phostine PST3.1a Targets MGAT5 and Inhibits Glioblastoma-Initiating Cell Invasiveness and Proliferation.
Mol Cancer Res
; 15(10): 1376-1387, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28634226
19.
Lactococcus lactis is an Efficient Expression System for Mammalian Membrane Proteins Involved in Liver Detoxification, CYP3A4, and MGST1.
Mol Biotechnol
; 58(4): 299-310, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26961909
20.
Safety and pharmacokinetics of the CIME combination of drugs and their metabolites after a single oral dosing in healthy volunteers.
Eur J Drug Metab Pharmacokinet
; 41(2): 125-38, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25465228