Detalhe da pesquisa
1.
Efficacy of oral 20-hydroxyecdysone (BIO101), a MAS receptor activator, in adults with severe COVID-19 (COVA): a randomized, placebo-controlled, phase 2/3 trial.
EClinicalMedicine
; 68: 102383, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38545090
2.
A Phase 1 study for safety and pharmacokinetics of BIO101 (20-hydroxyecdysone) in healthy young and older adults.
J Cachexia Sarcopenia Muscle
; 14(3): 1259-1273, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37057316
3.
Novel Potential Targets for Function-Promoting Therapies: Orphan Nuclear Receptors, Anti-inflammatory Drugs, Troponin Activators, Mas Receptor Agonists, and Urolithin A.
J Gerontol A Biol Sci Med Sci
; 78(Suppl 1): 44-52, 2023 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37325960
4.
Optimizing the Design of Clinical Trials to Evaluate the Efficacy of Function-Promoting Therapies.
J Gerontol A Biol Sci Med Sci
; 78(Suppl 1): 86-93, 2023 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37325959
5.
20-Hydroxyecdysone, from Plant Extracts to Clinical Use: Therapeutic Potential for the Treatment of Neuromuscular, Cardio-Metabolic and Respiratory Diseases.
Biomedicines
; 9(5)2021 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33947076
6.
A comparison between virus- versus patients-centred therapeutic attempts to reduce COVID-19 mortality.
Emerg Microbes Infect
; 10(1): 2256-2263, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34783636
7.
20-Hydroxyecdysone activates the protective arm of the RAAS via the MAS receptor.
J Mol Endocrinol
; 68(2): 77-87, 2021 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34825653
8.
Quinoa extract enriched in 20-hydroxyecdysone affects energy homeostasis and intestinal fat absorption in mice fed a high-fat diet.
Physiol Behav
; 128: 226-31, 2014 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24534167
9.
Quinoa extract enriched in 20-hydroxyecdysone protects mice from diet-induced obesity and modulates adipokines expression.
Obesity (Silver Spring)
; 20(2): 270-7, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21869758
10.
A test for ectopic exchange catalyzed by Cre recombinase in maize.
Theor Appl Genet
; 111(2): 378-85, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15912343
11.
A putative polyketide synthase/peptide synthetase from Magnaporthe grisea signals pathogen attack to resistant rice.
Plant Cell
; 16(9): 2499-513, 2004 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15319478