Detalhe da pesquisa
1.
Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing.
Cell
; 182(5): 1232-1251.e22, 2020 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32822576
2.
ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression.
Proc Natl Acad Sci U S A
; 120(8): e2216479120, 2023 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36791109
3.
Differential Chemoproteomics Reveals MARK2/3 as Cell Migration-Relevant Targets of the ALK Inhibitor Brigatinib.
Chembiochem
; 24(11): e202200766, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36922348
4.
Pralsetinib for RET fusion-positive non-small-cell lung cancer (ARROW): a multi-cohort, open-label, phase 1/2 study.
Lancet Oncol
; 22(7): 959-969, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34118197
5.
Novel Human-Derived RET Fusion NSCLC Cell Lines Have Heterogeneous Responses to RET Inhibitors and Differential Regulation of Downstream Signaling.
Mol Pharmacol
; 99(6): 435-447, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33795352
6.
Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children.
N Engl J Med
; 378(8): 731-739, 2018 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29466156
7.
Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1-2 trials.
Lancet Oncol
; 21(2): 271-282, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31838007
8.
Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1-2 trials.
Lancet Oncol
; 21(2): 261-270, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31838015
9.
Granulomatosis with polyangiitis in a patient treated with dabrafenib and trametinib for BRAF V600E positive lung adenocarcinoma.
BMC Cancer
; 20(1): 177, 2020 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32131760
10.
Randomized Phase II Trial of Seribantumab in Combination with Erlotinib in Patients with EGFR Wild-Type Non-Small Cell Lung Cancer.
Oncologist
; 24(8): 1095-1102, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30975923
11.
Rociletinib in EGFR-mutated non-small-cell lung cancer.
N Engl J Med
; 372(18): 1700-9, 2015 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25923550
12.
Triple Angiokinase Inhibitor Nintedanib Directly Inhibits Tumor Cell Growth and Induces Tumor Shrinkage via Blocking Oncogenic Receptor Tyrosine Kinases.
J Pharmacol Exp Ther
; 364(3): 494-503, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29263244
13.
Crizotinib in ROS1-rearranged non-small-cell lung cancer.
N Engl J Med
; 371(21): 1963-71, 2014 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25264305
14.
Non-Small Cell Lung Cancer, Version 5.2017, NCCN Clinical Practice Guidelines in Oncology.
J Natl Compr Canc Netw
; 15(4): 504-535, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28404761
15.
Local consolidative therapy versus maintenance therapy or observation for patients with oligometastatic non-small-cell lung cancer without progression after first-line systemic therapy: a multicentre, randomised, controlled, phase 2 study.
Lancet Oncol
; 17(12): 1672-1682, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27789196
16.
Phase 2, randomized, open-label study of ramucirumab in combination with first-line pemetrexed and platinum chemotherapy in patients with nonsquamous, advanced/metastatic non-small cell lung cancer.
Cancer
; 121(6): 883-92, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25377507
17.
The minority report: targeting the rare oncogenes in NSCLC.
Curr Treat Options Oncol
; 15(4): 644-57, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25228144
18.
Differential network analysis of ROS1 inhibitors reveals lorlatinib polypharmacology through co-targeting PYK2.
Cell Chem Biol
; 31(2): 284-297.e10, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37848034
19.
MIG6 Mediates Adaptive and Acquired Resistance to ALK/ROS1 Fusion Kinase Inhibition through EGFR Bypass Signaling.
Mol Cancer Ther
; 23(1): 92-105, 2024 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37748191
20.
Diagnostic assays for identification of anaplastic lymphoma kinase-positive non-small cell lung cancer.
Cancer
; 119(8): 1467-77, 2013 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23280244