Detalhe da pesquisa
1.
Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome.
Proc Natl Acad Sci U S A
; 118(39)2021 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34548400
2.
Dimeric Artesunate Glycerophosphocholine Conjugate Nano-Assemblies as Slow-Release Antimalarials to Overcome Kelch 13 Mutant Artemisinin Resistance.
Antimicrob Agents Chemother
; 66(5): e0206521, 2022 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35416709
3.
Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins.
J Cell Sci
; 129(2): 406-16, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26675237
4.
Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance.
PLoS Biol
; 13(4): e1002132, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25901609
5.
Comparison of untagged and his-tagged dihydrodipicolinate synthase from the enteric pathogen Vibrio cholerae.
Protein Expr Purif
; 145: 85-93, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29337198
6.
i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4.
J Biol Chem
; 291(24): 12641-12657, 2016 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27036939
7.
A Dynamic Stress Model Explains the Delayed Drug Effect in Artemisinin Treatment of Plasmodium falciparum.
Antimicrob Agents Chemother
; 61(12)2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28993326
8.
Disarming bacterial virulence through chemical inhibition of the DNA binding domain of an AraC-like transcriptional activator protein.
J Biol Chem
; 288(43): 31115-26, 2013 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24019519
9.
Identification of the bona fide DHDPS from a common plant pathogen.
Proteins
; 82(9): 1869-83, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24677246
10.
Defining the interaction of perforin with calcium and the phospholipid membrane.
Biochem J
; 456(3): 323-35, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24070258
11.
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Nat Commun
; 15(1): 937, 2024 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38297033
12.
Dimerization of plant defensin NaD1 enhances its antifungal activity.
J Biol Chem
; 287(24): 19961-72, 2012 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22511788
13.
Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition.
Plant Mol Biol
; 81(4-5): 431-46, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23354837
14.
Cloning to crystallization of dihydrodipicolinate synthase from the intracellular pathogen Legionella pneumophila.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 69(Pt 10): 1177-81, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24100576
15.
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Res Sq
; 2023 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37546892
16.
Comparative structure and function analyses of native and his-tagged forms of dihydrodipicolinate reductase from methicillin-resistant Staphylococcus aureus.
Protein Expr Purif
; 85(1): 66-76, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22776412
17.
Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from Agrobacterium tumefaciens.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 68(Pt 9): 1040-7, 2012 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22949190
18.
Characterization of a novel JNK (c-Jun N-terminal kinase) inhibitory peptide.
Biochem J
; 434(3): 399-413, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21162712
19.
Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax.
J Biol Chem
; 285(8): 5188-95, 2010 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-19948665
20.
Catalytic mechanism and cofactor preference of dihydrodipicolinate reductase from methicillin-resistant Staphylococcus aureus.
Arch Biochem Biophys
; 512(2): 167-74, 2011 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21704017