Pesquisa | Portal de Pesquisa da BVS

1.

Cytokine Regulation and Function in T Cells.

Dong, Chen.

Annu Rev Immunol ; 39: 51-76, 2021 04 26.

Artigo em Inglês | MEDLINE | ID: mdl-33428453

2.

IL-17D-induced inhibition of DDX5 expression in keratinocytes amplifies IL-36R-mediated skin inflammation.

Ni, Xinhui; Xu, Yi; Wang, Wang; Kong, Baida; Ouyang, Jian; Chen, Jiwei; Yan, Man; Wu, Yawei; Chen, Qi; Wang, Xinxin; Li, Hongquan; Gao, Xiaoguang; Guo, Hongquan; Cui, Lian; Chen, Zeyu; Shi, Yuling; Zhu, Ronghui; Li, Wei; Shi, Tieliu; Wang, Lin-Fa; Huang, Jinling; Dong, Chen; Lai, Yuping.

Nat Immunol ; 23(11): 1577-1587, 2022 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-36271146

3.

25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages.

Xiao, Jun; Wang, Shuang; Chen, Longlong; Ding, Xinyu; Dang, Yuanhao; Han, Mingshun; Zheng, Yuxiao; Shen, Huan; Wu, Sifan; Wang, Mingchang; Yang, Dan; Li, Na; Dong, Chen; Hu, Miao; Su, Chen; Li, Weiyun; Hui, Lijian; Ye, Youqiong; Tang, Huiru; Wei, Bin; Wang, Hongyan.

Immunity ; 57(5): 1087-1104.e7, 2024 May 14.

Artigo em Inglês | MEDLINE | ID: mdl-38640930

4.

Author Correction: Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment.

Yang, Xuexian O; Angkasekwinai, Pornpimon; Zhu, Jinfang; Peng, Juan; Liu, Zhiduo; Nurieva, Roza; Liu, Xikui; Chung, Yeonseok; Chang, Seon Hee; Sun, Bing; Dong, Chen.

Nat Immunol ; 21(11): 1467, 2020 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-32884131

5.

Costimulation molecules differentially regulate the ERK-Zfp831 axis to shape T follicular helper cell differentiation.

Wan, Siyuan; Ni, Lu; Zhao, Xiaohong; Liu, Xindong; Xu, Wei; Jin, Wei; Wang, Xiaohu; Dong, Chen.

Immunity ; 54(12): 2740-2755.e6, 2021 12 14.

Artigo em Inglês | MEDLINE | ID: mdl-34644536

6.

Interleukin-17D regulates group 3 innate lymphoid cell function through its receptor CD93.

Huang, Jinling; Lee, Hae-Youn; Zhao, Xiaohong; Han, Jinyi; Su, Yang; Sun, Qinli; Shao, Jing; Ge, Jiwan; Zhao, Yuxi; Bai, Xue; He, Yi; Wang, Xinquan; Wang, Xiaohu; Dong, Chen.

Immunity ; 54(4): 673-686.e4, 2021 04 13.

Artigo em Inglês | MEDLINE | ID: mdl-33852831

7.

The Conserved Non-coding Sequences CNS6 and CNS9 Control Cytokine-Induced Rorc Transcription during T Helper 17 Cell Differentiation.

Chang, Dehui; Xing, Qi; Su, Yang; Zhao, Xiaohong; Xu, Wei; Wang, Xiaohu; Dong, Chen.

Immunity ; 53(3): 614-626.e4, 2020 09 15.

Artigo em Inglês | MEDLINE | ID: mdl-32827457

8.

Febrile Temperature Critically Controls the Differentiation and Pathogenicity of T Helper 17 Cells.

Wang, Xiaohu; Ni, Lu; Wan, Siyuan; Zhao, Xiaohong; Ding, Xiao; Dejean, Anne; Dong, Chen.

Immunity ; 52(2): 328-341.e5, 2020 02 18.

Artigo em Inglês | MEDLINE | ID: mdl-32049050

9.

Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals.

Ni, Ling; Ye, Fang; Cheng, Meng-Li; Feng, Yu; Deng, Yong-Qiang; Zhao, Hui; Wei, Peng; Ge, Jiwan; Gou, Mengting; Li, Xiaoli; Sun, Lin; Cao, Tianshu; Wang, Pengzhi; Zhou, Chao; Zhang, Rongrong; Liang, Peng; Guo, Han; Wang, Xinquan; Qin, Cheng-Feng; Chen, Fang; Dong, Chen.

Immunity ; 52(6): 971-977.e3, 2020 06 16.

Artigo em Inglês | MEDLINE | ID: mdl-32413330

10.

The Transcription Factor Tox2 Drives T Follicular Helper Cell Development via Regulating Chromatin Accessibility.

Xu, Wei; Zhao, Xiaohong; Wang, Xiaoshuang; Feng, Han; Gou, Mengting; Jin, Wei; Wang, Xiaohu; Liu, Xindong; Dong, Chen.

Immunity ; 51(5): 826-839.e5, 2019 11 19.

Artigo em Inglês | MEDLINE | ID: mdl-31732165

11.

Mechanical Skin Injury Promotes Food Anaphylaxis by Driving Intestinal Mast Cell Expansion.

Leyva-Castillo, Juan-Manuel; Galand, Claire; Kam, Christy; Burton, Oliver; Gurish, Michael; Musser, Melissa A; Goldsmith, Jeffrey D; Hait, Elizabeth; Nurko, Samuel; Brombacher, Frank; Dong, Chen; Finkelman, Fred D; Lee, Richard T; Ziegler, Steven; Chiu, Isaac; Austen, K Frank; Geha, Raif S.

Immunity ; 50(5): 1262-1275.e4, 2019 05 21.

Artigo em Inglês | MEDLINE | ID: mdl-31027995

12.

Seventeen on inflammation.

Dong, Chen.

Nat Immunol ; 21(8): 821-822, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32616860

13.

An Interleukin-25-Mediated Autoregulatory Circuit in Keratinocytes Plays a Pivotal Role in Psoriatic Skin Inflammation.

Xu, Miao; Lu, Huiping; Lee, Young-Hee; Wu, Yelin; Liu, Kewei; Shi, Yuling; An, Haoran; Zhang, Jingren; Wang, Xiaohu; Lai, Yuping; Dong, Chen.

Immunity ; 48(4): 787-798.e4, 2018 04 17.

Artigo em Inglês | MEDLINE | ID: mdl-29653697

14.

Co-inhibitory Molecule B7 Superfamily Member 1 Expressed by Tumor-Infiltrating Myeloid Cells Induces Dysfunction of Anti-tumor CD8⁺ T Cells.

Li, Jing; Lee, Younghee; Li, Yanjian; Jiang, Yu; Lu, Huiping; Zang, Wenjuan; Zhao, Xiaohong; Liu, Liguo; Chen, Yang; Tan, Haidong; Yang, Zhiying; Zhang, Michael Q; Mak, Tak W; Ni, Ling; Dong, Chen.

Immunity ; 48(4): 773-786.e5, 2018 04 17.

Artigo em Inglês | MEDLINE | ID: mdl-29625896

15.

AKT2 reduces IFNß1 production to modulate antiviral responses and systemic lupus erythematosus.

Zheng, Xin; Xiao, Jun; Jiang, Qi; Zheng, Lingming; Liu, Chang; Dong, Chen; Zheng, Yuxiao; Ni, Peili; Zhang, Chi; Zhang, Fang; Zhong, Ruiyue; Ding, Huihua; Wang, Qiong; Qiu, Ying; Gao, Minxia; Ding, Jianping; Shen, Nan; Wei, Bin; Wang, Hongyan.

EMBO J ; 41(6): e108016, 2022 03 15.

Artigo em Inglês | MEDLINE | ID: mdl-35191555

16.

PPARα phosphorylation regulates colorectal tumor immune escape.

Gou, Qian; Tian, Xiaoqing; Dong, Chen; Yan, Bingjun; Chen, Mingjun; Shi, Juanjuan; Yang, Limin; Hou, Yongzhong.

J Biol Chem ; : 107447, 2024 Jun 04.

Artigo em Inglês | MEDLINE | ID: mdl-38844134

17.

The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation.

Yang, Xuexian O; Zhang, Huiyuan; Kim, Byung-Seok; Niu, Xiaoyin; Peng, Juan; Chen, Yuhong; Kerketta, Romica; Lee, Young-Hee; Chang, Seon Hee; Corry, David B; Wang, Demin; Watowich, Stephanie S; Dong, Chen.

Nat Immunol ; 14(7): 732-40, 2013 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-23727894

18.

Potato virus Y viral protein 6K1 inhibits the interaction between defense proteins during virus infection.

Fang, Le; Geng, Chao; Wei, Xin-Yu; Dong, Chen-Chen; Pang, Ju-Ping; Yan, Zhi-Yong; Jiang, Jun; Tian, Yan-Ping; Li, Xiang-Dong.

Plant Physiol ; 194(3): 1447-1466, 2024 Feb 29.

Artigo em Inglês | MEDLINE | ID: mdl-37962935

19.

The MicroRNA-183-96-182 Cluster Promotes T Helper 17 Cell Pathogenicity by Negatively Regulating Transcription Factor Foxo1 Expression.

Ichiyama, Kenji; Gonzalez-Martin, Alicia; Kim, Byung-Seok; Jin, Hyun Yong; Jin, Wei; Xu, Wei; Sabouri-Ghomi, Mohsen; Xu, Shunbin; Zheng, Pan; Xiao, Changchun; Dong, Chen.

Immunity ; 44(6): 1284-98, 2016 06 21.

Artigo em Inglês | MEDLINE | ID: mdl-27332731

20.

Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction.

Liu, Xindong; Wang, Yun; Lu, Huiping; Li, Jing; Yan, Xiaowei; Xiao, Minglu; Hao, Jing; Alekseev, Andrei; Khong, Hiep; Chen, Tenghui; Huang, Rui; Wu, Jin; Zhao, Qiwen; Wu, Qi; Xu, Senlin; Wang, Xiaohu; Jin, Wei; Yu, Shicang; Wang, Yan; Wei, Lai; Wang, Aibo; Zhong, Bo; Ni, Ling; Liu, Xiaolong; Nurieva, Roza; Ye, Lilin; Tian, Qiang; Bian, Xiu-Wu; Dong, Chen.

Nature ; 567(7749): 525-529, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30814730

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