Detalhe da pesquisa
1.
Efficacy and safety of maralixibat treatment in patients with Alagille syndrome and cholestatic pruritus (ICONIC): a randomised phase 2 study.
Lancet
; 398(10311): 1581-1592, 2021 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34755627
2.
Safety, tolerability and pharmacodynamics of apical sodium-dependent bile acid transporter inhibition with volixibat in healthy adults and patients with type 2 diabetes mellitus: a randomised placebo-controlled trial.
BMC Gastroenterol
; 18(1): 3, 2018 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29304731
3.
Single-dose, subcutaneous recombinant phenylalanine ammonia lyase conjugated with polyethylene glycol in adult patients with phenylketonuria: an open-label, multicentre, phase 1 dose-escalation trial.
Lancet
; 384(9937): 37-44, 2014 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24743000
4.
Phenotypes determined by cluster analysis in severe or difficult-to-treat asthma.
J Allergy Clin Immunol
; 133(6): 1549-56, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24315502
5.
Characterization of Fatigue in Primary Mitochondrial Myopathies: Findings From a Qualitative Interview Study.
Neurol Clin Pract
; 14(1): e200229, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38229875
6.
Safety, tolerability, and efficacy of maralixibat in adults with primary sclerosing cholangitis: Open-label pilot study.
Hepatol Commun
; 7(6)2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37184523
7.
Treatment of VLCAD-Deficient Patient Fibroblasts with Peroxisome Proliferator-Activated Receptor δ Agonist Improves Cellular Bioenergetics.
Cells
; 11(17)2022 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36078043
8.
Maralixibat for the treatment of PFIC: Long-term, IBAT inhibition in an open-label, Phase 2 study.
Hepatol Commun
; 6(9): 2379-2390, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35507739
9.
A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis.
Hepatol Commun
; 3(3): 365-381, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30859149
10.
Development of a Novel Tool to Assess the Impact of Itching in Pediatric Cholestasis.
Patient
; 11(1): 69-82, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28710680
11.
Impact of asthma exacerbations and asthma triggers on asthma-related quality of life in patients with severe or difficult-to-treat asthma.
J Allergy Clin Immunol Pract
; 2(5): 544-52.e1-2, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25213047
12.
Clinical burden and predictors of asthma exacerbations in patients on guideline-based steps 4-6 asthma therapy in the TENOR cohort.
J Allergy Clin Immunol Pract
; 2(2): 193-200, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24607048
13.
Chaperone-like therapy with tetrahydrobiopterin in clinical trials for phenylketonuria: is genotype a predictor of response?
JIMD Rep
; 5: 59-70, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23430918
14.
Assessment of asthma control and asthma exacerbations in the epidemiology and natural history of asthma: outcomes and treatment regimens (TENOR) observational cohort.
Curr Respir Care Rep
; 1(4): 259-269, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23136642
15.
Efficacy and safety of heparinase I versus protamine in patients undergoing coronary artery bypass grafting with and without cardiopulmonary bypass.
Anesthesiology
; 103(2): 229-40, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16052104
16.
Predose infant nevirapine concentration with the two-dose intrapartum neonatal nevirapine regimen: association with timing of maternal intrapartum nevirapine dose.
J Acquir Immune Defic Syndr
; 33(2): 153-6, 2003 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12794547
17.
When the time comes to talk about HIV: factors associated with diagnostic disclosure and emotional distress in HIV-infected children.
J Acquir Immune Defic Syndr
; 31(3): 309-17, 2002 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12439206
18.
Maternal toxicity and pregnancy complications in human immunodeficiency virus-infected women receiving antiretroviral therapy: PACTG 316.
Am J Obstet Gynecol
; 190(2): 506-16, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-14981398
19.
Two-dose intrapartum/newborn nevirapine and standard antiretroviral therapy to reduce perinatal HIV transmission: a randomized trial.
JAMA
; 288(2): 189-98, 2002 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-12095383
20.
Development of resistance mutations in women receiving standard antiretroviral therapy who received intrapartum nevirapine to prevent perinatal human immunodeficiency virus type 1 transmission: a substudy of pediatric AIDS clinical trials group protocol 316.
J Infect Dis
; 186(2): 181-8, 2002 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12134253