Detalhe da pesquisa
1.
Loss of epigenetic information as a cause of mammalian aging.
Cell
; 186(2): 305-326.e27, 2023 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36638792
2.
Loss of epigenetic information as a cause of mammalian aging.
Cell
; 187(5): 1312-1313, 2024 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38428398
3.
Airway hillocks are injury-resistant reservoirs of unique plastic stem cells.
Nature
; 629(8013): 869-877, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38693267
4.
Apoptotic stress causes mtDNA release during senescence and drives the SASP.
Nature
; 622(7983): 627-636, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37821702
5.
Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence.
Genes Dev
; 34(5-6): 428-445, 2020 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32001510
6.
Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence.
Mol Cell
; 73(4): 684-698.e8, 2019 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30773298
7.
Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML.
Blood
; 142(23): 2002-2015, 2023 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37738460
8.
Author Correction: Apoptotic stress causes mtDNA release during senescence and drives the SASP.
Nature
; 625(7995): E15, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38168624
9.
TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis.
Mol Cell
; 61(5): 720-733, 2016 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26942676
10.
MLL1 is essential for the senescence-associated secretory phenotype.
Genes Dev
; 30(3): 321-36, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26833731
11.
Cytoplasmic chromatin triggers inflammation in senescence and cancer.
Nature
; 550(7676): 402-406, 2017 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28976970
12.
Autophagy mediates degradation of nuclear lamina.
Nature
; 527(7576): 105-9, 2015 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26524528
13.
Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth.
Nature
; 525(7568): 206-11, 2015 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26331536
14.
Class IA PI3K p110ß subunit promotes autophagy through Rab5 small GTPase in response to growth factor limitation.
Mol Cell
; 50(1): 29-42, 2013 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23434372
15.
Combinatorial genetics in liver repopulation and carcinogenesis with a in vivo CRISPR activation platform.
Hepatology
; 68(2): 663-676, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29091290
16.
TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis.
Mol Cell
; 62(1): 149-51, 2016 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27058791
17.
Lysine methylation represses p53 activity in teratocarcinoma cancer cells.
Proc Natl Acad Sci U S A
; 113(35): 9822-7, 2016 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27535933
18.
Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase-activating protein Armus.
J Cell Sci
; 129(23): 4424-4435, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27793976
19.
Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.
PLoS Genet
; 10(10): e1004626, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25275521
20.
TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I-like receptor-mediated innate immune response.
Proc Natl Acad Sci U S A
; 111(2): E245-54, 2014 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24379373