Detalhe da pesquisa
1.
Decoupling of catalysis and transition state analog binding from mutations throughout a phosphatase revealed by high-throughput enzymology.
Proc Natl Acad Sci U S A
; 120(29): e2219074120, 2023 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37428919
2.
Assessment of enzyme active site positioning and tests of catalytic mechanisms through X-ray-derived conformational ensembles.
Proc Natl Acad Sci U S A
; 117(52): 33204-33215, 2020 12 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33376217
3.
Crystal structure of the m4-1BB/4-1BBL complex reveals an unusual dimeric ligand that undergoes structural changes upon 4-1BB receptor binding.
J Biol Chem
; 294(6): 1831-1845, 2019 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30545939
4.
Structure of human cytomegalovirus UL144, an HVEM orthologue, bound to the B and T cell lymphocyte attenuator.
J Biol Chem
; 294(27): 10519-10529, 2019 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31126984
5.
Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier.
J Biol Chem
; 293(26): 9958-9969, 2018 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29720398
6.
Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.
J Biol Chem
; 293(4): 1317-1329, 2018 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29242193
7.
Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8.
J Biol Chem
; 293(1): 390-401, 2018 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29123031
8.
Crystal structure of the pristine peroxidase ferryl center and its relevance to proton-coupled electron transfer.
Proc Natl Acad Sci U S A
; 113(5): 1226-31, 2016 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26787871
9.
Differential catalytic promiscuity of the alkaline phosphatase superfamily bimetallo core reveals mechanistic features underlying enzyme evolution.
J Biol Chem
; 292(51): 20960-20974, 2017 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29070681
10.
Structural Coupling Throughout the Active Site Hydrogen Bond Networks of Ketosteroid Isomerase and Photoactive Yellow Protein.
J Am Chem Soc
; 140(31): 9827-9843, 2018 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29990421
11.
Visualizing molecular juggling within a B12-dependent methyltransferase complex.
Nature
; 484(7393): 265-9, 2012 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22419154
12.
Crystal structure of the Leishmania major peroxidase-cytochrome c complex.
Proc Natl Acad Sci U S A
; 109(45): 18390-4, 2012 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23100535
13.
Temperature-dependent iron motion in extremophile rubredoxins - no need for 'corresponding states'.
Sci Rep
; 14(1): 12197, 2024 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38806591
14.
Structural changes that occur upon photolysis of the Fe(II)(a3)-CO complex in the cytochrome ba(3)-oxidase of Thermus thermophilus: a combined X-ray crystallographic and infrared spectral study demonstrates CO binding to Cu(B).
Biochim Biophys Acta
; 1817(4): 658-65, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22226917
15.
Regulation of the intersubunit ammonia tunnel in Mycobacterium tuberculosis glutamine-dependent NAD+ synthetase.
Biochem J
; 443(2): 417-26, 2012 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22280445
16.
Obtaining anomalous and ensemble information from protein crystals from 220â K up to physiological temperatures.
Acta Crystallogr D Struct Biol
; 79(Pt 3): 212-223, 2023 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36876431
17.
Refinement of Multiconformer Ensemble Models from Multi-temperature X-ray Diffraction Data.
bioRxiv
; 2023 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37205593
18.
Refinement of multiconformer ensemble models from multi-temperature X-ray diffraction data.
Methods Enzymol
; 688: 223-254, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37748828
19.
Structure of the Sec14 domain of Kalirin reveals a distinct class of lipid-binding module in RhoGEFs.
Nat Commun
; 14(1): 96, 2023 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36609407
20.
Decreasing the flexibility of the TELSAM-target protein linker and omitting the cleavable fusion tag improves crystal order and diffraction limits.
bioRxiv
; 2023 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37293010