Detalhe da pesquisa
1.
RNAi screen reveals synthetic lethality between cyclin G-associated kinase and FBXW7 by inducing aberrant mitoses.
Br J Cancer
; 117(7): 954-964, 2017 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28829765
2.
Discovery of 2-(3-Benzamidopropanamido)thiazole-5-carboxylate Inhibitors of the Kinesin HSET (KIFC1) and the Development of Cellular Target Engagement Probes.
J Med Chem
; 66(4): 2622-2645, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36749938
3.
A cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2.
J Biol Chem
; 284(48): 33177-84, 2009 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19801554
4.
Integration of RNAi and Small Molecule Screens to Identify Targets for Drug Development.
Methods Mol Biol
; 1953: 33-42, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30912014
5.
High Proliferation Rate and a Compromised Spindle Assembly Checkpoint Confers Sensitivity to the MPS1 Inhibitor BOS172722 in Triple-Negative Breast Cancers.
Mol Cancer Ther
; 18(10): 1696-1707, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31575759
6.
Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts.
Mol Cancer Ther
; 6(9): 2591-9, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17876056
7.
Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer.
Nat Commun
; 9(1): 1044, 2018 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29535384
8.
APC/C is an essential regulator of centrosome clustering.
Nat Commun
; 5: 3686, 2014 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24751481
9.
Integration of RNAi and small molecule screens to identify targets for drug development.
Methods Mol Biol
; 986: 97-104, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23436408
10.
Multifaceted targeting in cancer: the recent cell death players meet the usual oncogene suspects.
Expert Opin Ther Targets
; 11(5): 641-59, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17465723
11.
Microarray analysis of the differential transformation mediated by Kirsten and Harvey Ras oncogenes in a human colorectal adenocarcinoma cell line.
Int J Cancer
; 118(3): 616-27, 2006 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16152623
12.
Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway.
J Biol Chem
; 280(24): 22856-67, 2005 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-15757891