Detalhe da pesquisa
1.
Fragment screening for drug leads by weak affinity chromatography (WAC-MS).
Methods
; 146: 26-38, 2018 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29378316
2.
Lipodisks integrated with weak affinity chromatography enable fragment screening of integral membrane proteins.
Analyst
; 141(3): 981-8, 2016 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26673836
3.
Comparison of weak affinity chromatography and surface plasmon resonance in determining affinity of small molecules.
Anal Biochem
; 461: 57-9, 2014 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24915639
4.
Engineering a tunable micropattern-array assay to sort single extracellular vesicles and particles to detect RNA and protein in situ.
J Extracell Vesicles
; 12(11): e12369, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37908159
5.
Weak affinity chromatography as a new approach for fragment screening in drug discovery.
Anal Biochem
; 414(1): 138-46, 2011 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21352794
6.
Toward high-throughput drug screening on a chip-based parallel affinity separation platform.
J Sep Sci
; 33(17-18): 2575-81, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20730836
7.
Pharmaceutical modulation of the proteolytic profile of Transforming Growth Factor Beta induced protein (TGFBIp) offers a new avenue for treatment of TGFBI-corneal dystrophy.
J Adv Res
; 24: 529-543, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32637173
8.
Analysis of Protein Target Interactions of Synthetic Mixtures by Affinity-LC/MS.
SLAS Discov
; 22(4): 440-446, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28328315
9.
Design and Synthesis of Ligand Efficient Dual Inhibitors of Janus Kinase (JAK) and Histone Deacetylase (HDAC) Based on Ruxolitinib and Vorinostat.
J Med Chem
; 60(20): 8336-8357, 2017 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28953386
10.
Weak affinity chromatography for evaluation of stereoisomers in early drug discovery.
J Biomol Screen
; 18(6): 748-55, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23479356
11.
High-throughput fragment screening by affinity LC-MS.
J Biomol Screen
; 18(2): 160-71, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22983162