Detalhe da pesquisa
1.
Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress.
Proc Natl Acad Sci U S A
; 121(10): e2313540121, 2024 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38416681
2.
A light-inducible protein clustering system for in vivo analysis of α-synuclein aggregation in Parkinson disease.
PLoS Biol
; 20(3): e3001578, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35263320
3.
MerTK is a mediator of alpha-synuclein fibril uptake by human microglia.
Brain
; 147(2): 427-443, 2024 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37671615
4.
The use of a SOX10 reporter toward ameliorating oligodendrocyte lineage differentiation from human induced pluripotent stem cells.
Glia
; 72(6): 1165-1182, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38497409
5.
GALC variants affect galactosylceramidase enzymatic activity and risk of Parkinson's disease.
Brain
; 146(5): 1859-1872, 2023 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36370000
6.
Neuroanatomical and cognitive biomarkers of alpha-synuclein propagation in a mouse model of synucleinopathy prior to onset of motor symptoms.
J Neurochem
; 2023 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37804203
7.
Microfabricated disk technology: Rapid scale up in midbrain organoid generation.
Methods
; 203: 465-477, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34314827
8.
An approach to measuring protein turnover in human induced pluripotent stem cell organoids by mass spectrometry.
Methods
; 203: 17-27, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35331912
9.
A streamlined CRISPR workflow to introduce mutations and generate isogenic iPSCs for modeling amyotrophic lateral sclerosis.
Methods
; 203: 297-310, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34500068
10.
The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications.
Genes Dev
; 29(10): 989-99, 2015 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25995186
11.
Transcriptional Dysregulation and Impaired Neuronal Activity in FMR1 Knock-Out and Fragile X Patients' iPSC-Derived Models.
Int J Mol Sci
; 24(19)2023 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37834379
12.
Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo.
Acta Neuropathol
; 144(5): 881-910, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36121476
13.
TNF receptor-associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation.
J Biol Chem
; 295(12): 3808-3825, 2020 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32029478
14.
USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin.
EMBO J
; 33(21): 2473-91, 2014 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25216678
15.
The E3 ubiquitin ligase parkin is recruited to the 26 S proteasome via the proteasomal ubiquitin receptor Rpn13.
J Biol Chem
; 290(12): 7492-505, 2015 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25666615
16.
Generation of human iPSC-derived phrenic-like motor neurons to model respiratory motor neuron degeneration in ALS.
Commun Biol
; 7(1): 238, 2024 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38418587
17.
The 37TrillionCells initiative for improving global healthcare via cell-based interception and precision medicine: focus on neurodegenerative diseases.
Mol Brain
; 17(1): 18, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38605409
18.
Illumination of understudied ciliary kinases.
Front Mol Biosci
; 11: 1352781, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38523660
19.
Secondary deficiency of neuraminidase 1 contributes to CNS pathology in neurological mucopolysaccharidoses via hypersialylation of brain glycoproteins.
bioRxiv
; 2024 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38712143
20.
An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders.
Mol Neurodegener
; 19(1): 31, 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38576039