Detalhe da pesquisa
1.
Simultaneous inhibition of endocytic recycling and lysosomal fusion sensitizes cells and tissues to oligonucleotide therapeutics.
Nucleic Acids Res
; 51(4): 1583-1599, 2023 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36727438
2.
A high dose KRP203 induces cytoplasmic vacuoles associated with altered phosphoinositide segregation and endosome expansion.
Biochem Biophys Res Commun
; 718: 149981, 2024 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38735134
3.
Diversifying faculty recruitment in biomedical sciences.
FASEB J
; 37(11): e23224, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37779389
4.
Disruption of the Rab7-Dependent Final Common Pathway of Endosomal and Autophagic Processing Results in a Severe Podocytopathy.
J Am Soc Nephrol
; 34(7): 1191-1206, 2023 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37022133
5.
Dynamic Phosphoproteomics Uncovers Signaling Pathways Modulated by Anti-oncogenic Sphingolipid Analogs.
Mol Cell Proteomics
; 18(3): 408-422, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30482847
6.
Sphingolipids inhibit endosomal recycling of nutrient transporters by inactivating ARF6.
J Cell Sci
; 131(12)2018 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29848659
7.
Biocompatible Chemotherapy for Leukemia by Acid-Cleavable, PEGylated FTY720.
Bioconjug Chem
; 31(3): 673-684, 2020 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31986014
8.
Design, synthesis and anticancer activity of constrained sphingolipid-phenoxazine/phenothiazine hybrid constructs targeting protein phosphatase 2A.
Bioorg Med Chem Lett
; 29(18): 2681-2685, 2019 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31383588
9.
Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase-activating protein Armus.
J Cell Sci
; 129(23): 4424-4435, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27793976
10.
B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.
J Immunol
; 194(7): 3065-78, 2015 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25740947
11.
Oligodendroglial deletion of ESCRT-I component TSG101 causes spongiform encephalopathy.
Biol Cell
; 108(11): 324-337, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27406702
12.
Effects of stereochemistry, saturation, and hydrocarbon chain length on the ability of synthetic constrained azacyclic sphingolipids to trigger nutrient transporter down-regulation, vacuolation, and cell death.
Bioorg Med Chem
; 24(18): 4390-4397, 2016 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27475534
13.
Targeting cancer metabolism at the plasma membrane by limiting amino acid access through SLC6A14.
Biochem J
; 470(3): e17-9, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26341486
14.
The complex interplay between autophagy, apoptosis, and necrotic signals promotes T-cell homeostasis.
Immunol Rev
; 236: 95-109, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20636811
15.
Rab7a activation promotes degradation of select tight junction proteins at the blood-brain barrier after ischemic stroke.
bioRxiv
; 2023 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37693406
16.
Defective autophagy leads to cancer.
Cancer Cell
; 4(6): 422-4, 2003 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-14706333
17.
Sphingolipid-based drugs selectively kill cancer cells by down-regulating nutrient transporter proteins.
Biochem J
; 439(2): 299-311, 2011 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21767261
18.
Differential effects of TBC1D15 and mammalian Vps39 on Rab7 activation state, lysosomal morphology, and growth factor dependence.
J Biol Chem
; 285(22): 16814-21, 2010 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20363736
19.
The BCL-2 protein BAK is required for long-chain ceramide generation during apoptosis.
J Biol Chem
; 285(16): 11818-26, 2010 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20172858
20.
Death by design: apoptosis, necrosis and autophagy.
Curr Opin Cell Biol
; 16(6): 663-9, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-15530778