Detalhe da pesquisa
1.
Effect of Aging and a Dual Orexin Receptor Antagonist on Sleep Architecture and Non-REM Oscillations Including an REM Behavior Disorder Phenotype in the PS19 Mouse Model of Tauopathy.
J Neurosci
; 43(25): 4738-4749, 2023 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37230765
2.
Proteomic analysis of X-linked dystonia parkinsonism disease striatal neurons reveals altered RNA metabolism and splicing.
Neurobiol Dis
; 190: 106367, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38042508
3.
Dystonia-specific mutations in THAP1 alter transcription of genes associated with neurodevelopment and myelin.
Am J Hum Genet
; 108(11): 2145-2158, 2021 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34672987
4.
TYROBP/DAP12 knockout in Huntington's disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterioration.
J Neuroinflammation
; 21(1): 66, 2024 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38459557
5.
miR155, TREM2, INPP5D: Disease stage and cell type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer's amyloidopathy.
J Neuroinflammation
; 20(1): 214, 2023 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37749581
6.
Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease.
Alzheimers Dement
; 19(6): 2239-2252, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36448627
7.
Abnormal cerebellar function and tremor in a mouse model for non-manifesting partially penetrant dystonia type 6.
J Physiol
; 599(7): 2037-2054, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33369735
8.
Moving the Needle on Alzheimer's Disease with an Anti-Oligomer Antibody.
N Engl J Med
; 388(1): 80-81, 2023 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36599066
9.
An atlas of chromatin accessibility in the adult human brain.
Genome Res
; 28(8): 1243-1252, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29945882
10.
Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.
Mov Disord
; 36(12): 2780-2794, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34403156
11.
Striatal Dopamine Induced ERK Phosphorylation Is Altered in Mouse Models of Monogenic Dystonia.
Mov Disord
; 36(5): 1147-1157, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33458877
12.
Mutations in THAP1/DYT6 reveal that diverse dystonia genes disrupt similar neuronal pathways and functions.
PLoS Genet
; 14(1): e1007169, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29364887
13.
Reactive or transgenic increase in microglial TYROBP reveals a TREM2-independent TYROBP-APOE link in wild-type and Alzheimer's-related mice.
Alzheimers Dement
; 17(2): 149-163, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33314529
14.
Diverse Mechanisms Lead to Common Dysfunction of Striatal Cholinergic Interneurons in Distinct Genetic Mouse Models of Dystonia.
J Neurosci
; 39(36): 7195-7205, 2019 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31320448
15.
Buprenorphine for the Treatment of the Neonatal Abstinence Syndrome.
N Engl J Med
; 376(24): 2341-2348, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28468518
16.
miR155 regulation of behavior, neuropathology, and cortical transcriptomics in Alzheimer's disease.
Acta Neuropathol
; 140(3): 295-315, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32666270
17.
Correction: Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aß amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aß burden.
Mol Psychiatry
; 24(3): 472, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30464330
18.
Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau.
Mol Psychiatry
; 24(9): 1383-1397, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30283031
19.
Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aß amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aß burden.
Mol Psychiatry
; 24(3): 431-446, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30283032
20.
Neurobehavioral effects of neonatal opioid exposure in mice: Influence of the OPRM1 SNP.
Addict Biol
; 25(5): e12806, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31267641