Detalhe da pesquisa
1.
Prostaglandin production selectively in brain endothelial cells is both necessary and sufficient for eliciting fever.
Proc Natl Acad Sci U S A
; 119(43): e2122562119, 2022 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36252026
2.
Fever During Localized Inflammation in Mice Is Elicited by a Humoral Pathway and Depends on Brain Endothelial Interleukin-1 and Interleukin-6 Signaling and Central EP3 Receptors.
J Neurosci
; 41(24): 5206-5218, 2021 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33941650
3.
The generation of immune-induced fever and emotional stress-induced hyperthermia in mice does not involve brown adipose tissue thermogenesis.
FASEB J
; 34(4): 5863-5876, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32144818
4.
Immune-Induced Fever Is Dependent on Local But Not Generalized Prostaglandin E2 Synthesis in the Brain.
J Neurosci
; 37(19): 5035-5044, 2017 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28438967
5.
Involvement of interleukin-1 type 1 receptors in lipopolysaccharide-induced sickness responses.
Brain Behav Immun
; 66: 165-176, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28655587
6.
Immune-induced fever is mediated by IL-6 receptors on brain endothelial cells coupled to STAT3-dependent induction of brain endothelial prostaglandin synthesis.
J Neurosci
; 34(48): 15957-61, 2014 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25429137
7.
Deletion of prostaglandin E2 synthesizing enzymes in brain endothelial cells attenuates inflammatory fever.
J Neurosci
; 34(35): 11684-90, 2014 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25164664
8.
Inflammation- and tumor-induced anorexia and weight loss require MyD88 in hematopoietic/myeloid cells but not in brain endothelial or neural cells.
FASEB J
; 27(5): 1973-80, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23395911
9.
Interleukin-1ß induced activation of the hypothalamus-pituitary-adrenal axis is dependent on interleukin-1 receptors on non-hematopoietic cells.
Brain Behav Immun
; 40: 166-73, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24681250
10.
Interleukin-6 primarily produced by non-hematopoietic cells mediates the lipopolysaccharide-induced febrile response.
Brain Behav Immun
; 33: 123-30, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23827828
11.
Prostaglandin production in brain endothelial cells during the initiation of fever.
Commun Integr Biol
; 16(1): 2166237, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36644132
12.
Distribution of microsomal prostaglandin E synthase-1 in the mouse brain.
J Comp Neurol
; 522(14): 3229-44, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24668417
13.
Acetaminophen reduces lipopolysaccharide-induced fever by inhibiting cyclooxygenase-2.
Neuropharmacology
; 71: 124-9, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23545161
14.
Lipopolysaccharide-induced fever depends on prostaglandin E2 production specifically in brain endothelial cells.
Endocrinology
; 153(10): 4849-61, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22872578