Detalhe da pesquisa
1.
Determining the safety of the tobacco cembranoid (1S,2E,4R,6R,7E,11E)-Cembratriene-4,6-diol (4R): A translational study in nonhuman primates.
Toxicol Appl Pharmacol
; 482: 116772, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38036230
2.
Neuroprotection Against Diisopropylfluorophosphate in Acute Hippocampal Slices.
Neurochem Res
; 40(10): 2143-51, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26438150
3.
Paraoxon and Pyridostigmine Interfere with Neural Stem Cell Differentiation.
Neurochem Res
; 40(10): 2091-101, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25758980
4.
Anti-hyperalgesic and anti-inflammatory effects of 4R-tobacco cembranoid in a mouse model of inflammatory pain.
J Inflamm (Lond)
; 21(1): 2, 2024 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38267952
5.
γ-Aminobutyric acid type A receptor inhibition triggers a nicotinic neuroprotective mechanism.
J Neurosci Res
; 91(3): 416-25, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23280428
6.
Protective activity of (1S,2E,4R,6R,7E,11E)-2,7,11-cembratriene-4,6-diol analogues against diisopropylfluorophosphate neurotoxicity: preliminary structure-activity relationship and pharmacophore modeling.
Bioorg Med Chem
; 21(15): 4678-86, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23769165
7.
In Vivo Evaluation of the Acute Systemic Toxicity of (1S,2E,4R,6R,7E,11E)-Cembratriene-4,6-diol (4R) in Sprague Dawley Rats.
Nutraceuticals (Basel)
; 2(2): 60-70, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35855209
8.
Memantine has a nicotinic neuroprotective pathway in acute hippocampal slices after an NMDA insult.
Toxicol In Vitro
; 84: 105453, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35944748
9.
Preface for the Special Issue Prof. Lynn Wecker.
Neurochem Res
; 40(10): 2007-8, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26526302
10.
4R-Cembranoid Improves Outcomes after 6-Hydroxydopamine Challenge in Both In vitro and In vivo Models of Parkinson's Disease.
Front Neurosci
; 11: 272, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28611572
11.
Pharmacokinetics and Metabolism of 4R-Cembranoid.
PLoS One
; 10(3): e0121540, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25811857
12.
Neuroprotective activity of (1S,2E,4R,6R,-7E,11E)-2,7,11-cembratriene-4,6-diol (4R) in vitro and in vivo in rodent models of brain ischemia.
Neuroscience
; 291: 250-259, 2015 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25677097
13.
Differential inhibition of nicotine- and acetylcholine-evoked currents through alpha4beta2 neuronal nicotinic receptors by tobacco cembranoids in Xenopus oocytes.
Neurosci Lett
; 366(1): 97-102, 2004 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-15265598
14.
4R-cembranoid protects against diisopropylfluorophosphate-mediated neurodegeneration.
Neurotoxicology
; 44: 80-90, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24928201
15.
Kinin-B2 receptor mediated neuroprotection after NMDA excitotoxicity is reversed in the presence of kinin-B1 receptor agonists.
PLoS One
; 7(2): e30755, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22348022
16.
Acute neuronal injury and blood genomic profiles in a nonhuman primate model for ischemic stroke.
Comp Med
; 62(5): 427-38, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23114047
17.
A cembranoid protects acute hippocampal slices against paraoxon neurotoxicity.
Toxicol In Vitro
; 25(7): 1468-74, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21569834
18.
Alpha 7 nicotinic acetylcholine receptor expression and activity during neuronal differentiation of PC12 pheochromocytoma cells.
J Mol Neurosci
; 41(3): 329-39, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20461497
19.
Actions of octocoral and tobacco cembranoids on nicotinic receptors.
Toxicon
; 54(8): 1174-82, 2009 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19281835
20.
A cembranoid from tobacco prevents the expression of nicotine-induced withdrawal behavior in planarian worms.
Eur J Pharmacol
; 615(1-3): 118-24, 2009 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19490913