Detalhe da pesquisa
1.
Discovery of novel ureas and thioureas of 3-decladinosyl-3-hydroxy 15-membered azalides active against efflux-mediated resistant Streptococcus pneumoniae.
Bioorg Med Chem Lett
; 21(2): 853-6, 2011 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21185182
2.
Synthesis and activity of new macrolones: conjugates between 6(7)-(2'-aminoethyl)-amino-1-cyclopropyl-3-carboxylic acid (2'-hydroxyethyl) amides and 4â³-propenoyl-azithromycin.
Bioorg Med Chem
; 19(23): 7270-80, 2011 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22041174
3.
Synthesis of macrolones with central piperazine ring in the linker and its influence on antibacterial activity.
Bioorg Med Chem
; 19(23): 7281-98, 2011 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22047805
4.
Macrolide Inspired Macrocycles as Modulators of the IL-17A/IL-17RA Interaction.
J Med Chem
; 64(12): 8354-8383, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34100601
5.
A novel class of fast-acting antimalarial agents: Substituted 15-membered azalides.
Br J Pharmacol
; 178(2): 363-377, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33085774
6.
Novel hybrids of 15-membered 8a- and 9a-azahomoerythromycin A ketolides and quinolones as potent antibacterials.
Bioorg Med Chem
; 18(24): 8566-82, 2010 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21055953
7.
Macrolide Hybrid Compounds: Drug Discovery Opportunities in Anti- Infective and Anti-inflammatory Area.
Curr Top Med Chem
; 17(8): 919-940, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27697049
8.
Synthesis and antibacterial activity of isomeric 15-membered azalides.
J Antibiot (Tokyo)
; 59(12): 753-69, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17323642
9.
Structure-property relationship for cellular accumulation of macrolones in human polymorphonuclear leukocytes (PMNs).
Eur J Pharm Sci
; 49(2): 206-19, 2013 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23474356
10.
Antimalarial activity of 9a-N substituted 15-membered azalides with improved in vitro and in vivo activity over azithromycin.
J Med Chem
; 55(3): 1389-401, 2012 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22148880
11.
Synthesis, activity and pharmacokinetics of novel antibacterial 15-membered ring macrolones.
Eur J Med Chem
; 46(8): 3388-97, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21600677
12.
Synthesis, structure-activity relationship, and antimalarial activity of ureas and thioureas of 15-membered azalides.
J Med Chem
; 54(10): 3595-605, 2011 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21476508
13.
Synthesis and biological properties of 4''-O-acyl derivatives of 8a-Aza-8a-homoerythromycin.
J Antibiot (Tokyo)
; 62(3): 133-44, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19218983