Detalhe da pesquisa
1.
Building C(sp3)-rich complexity by combining cycloaddition and C-C cross-coupling reactions.
Nature
; 560(7718): 350-354, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30061620
2.
Synthesis of a Polycyclic Halichondrin C1-C14 Fragment via Intermolecular Oxy-Michael/ Trans-Ketalization.
J Org Chem
; 84(8): 4898-4903, 2019 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30395467
3.
Stereoselective synthesis of the Halaven C14-C26 fragment from D-quinic acid: crystallization-induced diastereoselective transformation of an α-methyl nitrile.
Angew Chem Int Ed Engl
; 54(17): 5108-11, 2015 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25829352
4.
Pharmacologic Activation of STING in the Bladder Induces Potent Antitumor Immunity in Non-Muscle Invasive Murine Bladder Cancer.
Mol Cancer Ther
; 21(6): 914-924, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35313332
5.
Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines.
Nat Commun
; 12(1): 343, 2021 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33436639
6.
E7766, a Macrocycle-Bridged Stimulator of Interferon Genes (STING) Agonist with Potent Pan-Genotypic Activity.
ChemMedChem
; 16(11): 1740-1743, 2021 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33522135
7.
Synthesis of the Halichondrin C1-C15 Fragment from a Halaven C27-C35 Byproduct: Stereospecific Intramolecular Kishi Reduction.
Org Lett
; 20(14): 4295-4297, 2018 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29956939
8.
Correction: Pharmacologic Activation of STING in the Bladder Induces Potent Antitumor Immunity in Non-Muscle Invasive Murine Bladder Cancer.
Mol Cancer Ther
; 22(4): 551, 2023 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37009707
9.
In vitro and in vivo anticancer activities of synthetic (-)-laulimalide, a marine natural product microtubule stabilizing agent.
Anticancer Res
; 27(3B): 1509-18, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17595769
10.
Prins Reaction of Homoallenyl Alcohols: Access to Substituted Pyrans in the Halichondrin Series.
Org Lett
; 19(22): 6092-6095, 2017 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29077412
11.
Tubulin-based antimitotic mechanism of E7974, a novel analogue of the marine sponge natural product hemiasterlin.
Mol Cancer Ther
; 8(10): 2852-60, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19825803
12.
Synthesis and biological evaluation of (-)-laulimalide analogues.
Bioorg Med Chem Lett
; 14(3): 575-9, 2004 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-14741246