Detalhe da pesquisa
1.
Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis: The COMRADE Randomized, Phase 2A Clinical Trial.
Am J Respir Crit Care Med
; 205(10): 1228-1235, 2022 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35258443
2.
Drug Effect of Clofazimine on Persisters Explains an Unexpected Increase in Bacterial Load in Patients.
Antimicrob Agents Chemother
; 64(5)2020 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32122887
3.
A model-based analysis identifies differences in phenotypic resistance between in vitro and in vivo: implications for translational medicine within tuberculosis.
J Pharmacokinet Pharmacodyn
; 47(5): 421-430, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32488575
4.
Subcutaneous Marzeptacog Alfa (Activated) for On-Demand Treatment of Bleeding Events in Subjects With Hemophilia A or B With Inhibitors.
Clin Pharmacol Ther
; 115(3): 498-505, 2024 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38173172
5.
Model-Informed Support of Dose Selection for Prophylactic Treatment with Dalcinonacog Alfa in Adult and Paediatric Hemophilia B Patients.
Adv Ther
; 40(9): 3739-3750, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37341915
6.
Standards for model-based early bactericidal activity analysis and sample size determination in tuberculosis drug development.
Front Pharmacol
; 14: 1150243, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37124198
7.
Model-informed pediatric dose selection of marzeptacog alfa (activated): An exposure matching strategy.
CPT Pharmacometrics Syst Pharmacol
; 12(7): 977-987, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37042339
8.
Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug.
CPT Pharmacometrics Syst Pharmacol
; 11(12): 1628-1637, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36191169
9.
Difference in persistent tuberculosis bacteria between in vitro and sputum from patients: implications for translational predictions.
Sci Rep
; 10(1): 15537, 2020 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32968142
10.
Cough as Noninvasive Biomarker for Monitoring Tuberculosis Treatment: A Proof-of-Concept Study.
Ann Am Thorac Soc
; 20(12): 1822-1825, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37751498