Detalhe da pesquisa
1.
TDP-43 condensation properties specify its RNA-binding and regulatory repertoire.
Cell
; 184(18): 4680-4696.e22, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34380047
2.
Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell
; 173(3): 693-705.e22, 2018 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29677513
3.
Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation.
Mol Cell
; 69(3): 465-479.e7, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29358076
4.
A synergy between site-specific and transient interactions drives the phase separation of a disordered, low-complexity domain.
Proc Natl Acad Sci U S A
; 120(34): e2305625120, 2023 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37579155
5.
Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration.
EMBO J
; 40(3): e105001, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33349959
6.
Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics.
Mol Cell
; 65(6): 1044-1055.e5, 2017 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28306503
7.
Structure and interactions of prion-like domains in transcription factor Efg1 phase separation.
Biophys J
; 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38297837
8.
SARS-CoV-2 nucleocapsid protein phase-separates with RNA and with human hnRNPs.
EMBO J
; 39(24): e106478, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33200826
9.
Membrane bending by protein phase separation.
Proc Natl Acad Sci U S A
; 118(11)2021 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33688043
10.
The oncogenic transcription factor FUS-CHOP can undergo nuclear liquid-liquid phase separation.
J Cell Sci
; 134(17)2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34357401
11.
Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II.
Mol Cell
; 60(2): 231-41, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26455390
12.
TDP-43 α-helical structure tunes liquid-liquid phase separation and function.
Proc Natl Acad Sci U S A
; 117(11): 5883-5894, 2020 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32132204
13.
A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing.
EMBO J
; 37(5)2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29438978
14.
Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis.
EMBO J
; 37(11)2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29764981
15.
Weak binding to the A2RE RNA rigidifies hnRNPA2 RRMs and reduces liquid-liquid phase separation and aggregation.
Nucleic Acids Res
; 48(18): 10542-10554, 2020 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32870271
16.
A predictive coarse-grained model for position-specific effects of post-translational modifications.
Biophys J
; 120(7): 1187-1197, 2021 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33582133
17.
Phase separation of the LINE-1 ORF1 protein is mediated by the N-terminus and coiled-coil domain.
Biophys J
; 120(11): 2181-2191, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33798566
18.
The (un)structural biology of biomolecular liquid-liquid phase separation using NMR spectroscopy.
J Biol Chem
; 295(8): 2375-2384, 2020 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31911439
19.
Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity.
EMBO J
; 36(20): 2951-2967, 2017 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28790177
20.
The SH3 domain of Fyn kinase interacts with and induces liquid-liquid phase separation of the low-complexity domain of hnRNPA2.
J Biol Chem
; 293(51): 19522-19531, 2018 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30397184