Detalhe da pesquisa
1.
SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species.
Cell
; 177(3): 622-638.e22, 2019 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31002797
2.
Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice.
Nature
; 621(7977): 196-205, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37612507
3.
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.
EMBO J
; 41(21): e110393, 2022 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36215696
4.
Interspecies Differences in Proteome Turnover Kinetics Are Correlated With Life Spans and Energetic Demands.
Mol Cell Proteomics
; 20: 100041, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33639418
5.
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.
EMBO J
; 42(3): e113326, 2023 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36722290
6.
DNA double-strand break repair is impaired in presenescent Syrian hamster fibroblasts.
BMC Mol Biol
; 16: 18, 2015 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26458748
7.
Maintenance of genome sequence integrity in long- and short-lived rodent species.
Sci Adv
; 7(44): eabj3284, 2021 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34705500
8.
Short-term calorie restriction enhances DNA repair by non-homologous end joining in mice.
NPJ Aging Mech Dis
; 6: 9, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32864160
9.
Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties.
Nat Commun
; 11(1): 2376, 2020 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32398747
10.
SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair.
Aging (Albany NY)
; 12(12): 11165-11184, 2020 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32584788
11.
Immunofluorescence Analysis of γ-H2AX Foci in Mammalian Fibroblasts at Different Phases of the Cell Cycle.
Methods Mol Biol
; 1644: 187-194, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28710765
12.
Rapid Detection of Apoptosis in Cultured Mammalian Cells.
Methods Mol Biol
; 1644: 105-111, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28710756
13.
Rapid Detection of γ-H2AX by Flow Cytometry in Cultured Mammalian Cells.
Methods Mol Biol
; 1644: 129-138, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28710759
14.
Dynamics of γH2AX formation and elimination in mammalian cells after X-irradiation.
Biochimie
; 94(11): 2416-22, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22766016
15.
H2AX phosphorylation at the sites of DNA double-strand breaks in cultivated mammalian cells and tissues.
Clin Epigenetics
; 2(2): 283-97, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22704343
16.
Slow elimination of phosphorylated histone gamma-H2AX from DNA of terminally differentiated mouse heart cells in situ.
Biochem Biophys Res Commun
; 347(4): 1048-52, 2006 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-16857171