Detalhe da pesquisa
1.
Design, Synthesis, and Cytotoxic Assessment of New Haloperidol Analogues as Potential Anticancer Compounds Targeting Sigma Receptors.
Molecules
; 29(11)2024 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38893570
2.
De novo KCNA6 variants with attenuated KV 1.6 channel deactivation in patients with epilepsy.
Epilepsia
; 64(2): 443-455, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36318112
3.
Cytotoxicity Profiles and Neuroprotective Properties of the Novel Ifenprodil Analogues as Sigma Ligands.
Molecules
; 28(8)2023 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37110664
4.
Mutations in the Neuronal Vesicular SNARE VAMP2 Affect Synaptic Membrane Fusion and Impair Human Neurodevelopment.
Am J Hum Genet
; 104(4): 721-730, 2019 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30929742
5.
A homozygous MED11 C-terminal variant causes a lethal neurodegenerative disease.
Genet Med
; 24(10): 2194-2203, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36001086
6.
Design, synthesis and biological evaluation of novel aminopropylcarboxamide derivatives as sigma ligands.
Bioorg Med Chem Lett
; 72: 128860, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35724925
7.
Synthesis, Biological Evaluation and Computational Studies of New Hydrazide Derivatives Containing 1,3,4-Oxadiazole as Antitubercular Agents.
Int J Mol Sci
; 23(23)2022 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36499618
8.
Insights on peptide topology in the computational design of protein ligands: the example of lysozyme binding peptides.
Phys Chem Chem Phys
; 23(40): 23158-23172, 2021 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34617942
9.
Computational Evolution of Beta-2-Microglobulin Binding Peptides for Nanopatterned Surface Sensors.
Int J Mol Sci
; 22(2)2021 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33467468
10.
Exploring the use of leucine zippers for the generation of a new class of inclusion bodies for pharma and biotechnological applications.
Microb Cell Fact
; 19(1): 175, 2020 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32887587
11.
Biallelic mutations in neurofascin cause neurodevelopmental impairment and peripheral demyelination.
Brain
; 142(10): 2948-2964, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31501903
12.
Design, synthesis and antimycobacterial activity of benzoxazinone derivatives and open-ring analogues: Preliminary data and computational analysis.
Bioorg Med Chem Lett
; 29(17): 2468-2474, 2019 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31350124
13.
Binding affinity prediction of nanobody-protein complexes by scoring of molecular dynamics trajectories.
Phys Chem Chem Phys
; 20(5): 3438-3444, 2018 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29328338
14.
Computational design of cyclic peptides for the customized oriented immobilization of globular proteins.
Phys Chem Chem Phys
; 19(4): 2740-2748, 2017 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28059415
15.
Phase behaviour of self-assembled monolayers controlled by tuning physisorbed and chemisorbed states: A lattice-model view.
J Chem Phys
; 144(13): 134707, 2016 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27059585
16.
Computational Mutagenesis of Antibody Fragments: Disentangling Side Chains from ΔΔG Predictions.
J Chem Theory Comput
; 20(6): 2630-2642, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38445482
17.
Allelic heterogeneity and abnormal vesicle recycling in PLAA-related neurodevelopmental disorders.
Front Mol Neurosci
; 17: 1268013, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38650658
18.
Replica-exchange optimization of antibody fragments.
Comput Biol Chem
; 103: 107819, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36657284
19.
Antibody Affinity Maturation Using Computational Methods: From an Initial Hit to Small-Scale Expression of Optimized Binders.
Methods Mol Biol
; 2552: 333-359, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36346602
20.
Interplay between C1-inhibitor and group IIA secreted phospholipase A2 impairs their respective function.
Immunol Res
; 71(1): 70-82, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36385678