Detalhe da pesquisa
1.
Differential effects of itacitinib, fedratinib, and ruxolitinib in mouse models of hemophagocytic lymphohistiocytosis.
Blood
; 143(23): 2386-2400, 2024 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38446698
2.
Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy.
Mol Cancer
; 23(1): 123, 2024 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38849845
3.
Modeling and targeting of erythroleukemia by hematopoietic genome editing.
Blood
; 137(12): 1628-1640, 2021 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33512458
4.
Orthotopic patient-derived xenografts of paediatric solid tumours.
Nature
; 549(7670): 96-100, 2017 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28854174
5.
Baloxavir Treatment Delays Influenza B Virus Transmission in Ferrets and Results in Limited Generation of Drug-Resistant Variants.
Antimicrob Agents Chemother
; 65(11): e0113721, 2021 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34424039
6.
Simvastatin Hydroxy Acid Fails to Attain Sufficient Central Nervous System Tumor Exposure to Achieve a Cytotoxic Effect: Results of a Preclinical Cerebral Microdialysis Study.
Drug Metab Dispos
; 44(4): 591-4, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26802130
7.
Preclinical studies of 5-fluoro-2'-deoxycytidine and tetrahydrouridine in pediatric brain tumors.
J Neurooncol
; 126(2): 225-34, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26518542
8.
Pharmacokinetics and efficacy of the spleen tyrosine kinase inhibitor r406 after ocular delivery for retinoblastoma.
Pharm Res
; 31(11): 3060-72, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24906597
9.
RBM39 degrader invigorates natural killer cells to eradicate neuroblastoma despite cancer cell plasticity.
bioRxiv
; 2024 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38585889
10.
Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition.
Nat Commun
; 15(1): 3483, 2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38664416
11.
Biologic and clinical analysis of childhood gamma delta T-ALL identifies LMO2/STAG2 rearrangements as extremely high-risk.
Cancer Discov
; 2024 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38916500
12.
Combination of Ribociclib with BET-Bromodomain and PI3K/mTOR Inhibitors for Medulloblastoma Treatment In Vitro and In Vivo.
Mol Cancer Ther
; 22(1): 37-51, 2023 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36318650
13.
ATM inhibition enhances the efficacy of radiation across distinct molecular subgroups of pediatric high-grade glioma.
Neuro Oncol
; 25(10): 1828-1841, 2023 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36971093
14.
Biologic and clinical features of childhood gamma delta T-ALL: identification of STAG2/LMO2 γδ T-ALL as an extremely high risk leukemia in the very young.
medRxiv
; 2023 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37986997
15.
Combining SJ733, an oral ATP4 inhibitor of Plasmodium falciparum, with the pharmacokinetic enhancer cobicistat: An innovative approach in antimalarial drug development.
EBioMedicine
; 80: 104065, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35598441
16.
Vitamin D levels do not cause vitamin-drug interactions with dexamethasone or dasatinib in mice.
PLoS One
; 16(10): e0258579, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34669728
17.
The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma.
Nat Commun
; 12(1): 6468, 2021 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34753908
18.
Identification of small molecules that mitigate vincristine-induced neurotoxicity while sensitizing leukemia cells to vincristine.
Clin Transl Sci
; 14(4): 1490-1504, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33742760
19.
Safety, tolerability, pharmacokinetics, and antimalarial efficacy of a novel Plasmodium falciparum ATP4 inhibitor SJ733: a first-in-human and induced blood-stage malaria phase 1a/b trial.
Lancet Infect Dis
; 20(8): 964-975, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32275867
20.
Rhabdoid Tumors Are Sensitive to the Protein-Translation Inhibitor Homoharringtonine.
Clin Cancer Res
; 26(18): 4995-5006, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32631955