1.
Dokl Biochem Biophys
; 476(1): 337-339, 2017 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29101752
RESUMO
This is the first study to show that the formation of 14ß-hydroxylated derivatives of taxa-4(20),11-diene is a specific feature of in vitro cultured dedifferentiated yew cells that distinguishes them from intact plant cells. This may be due to a lower toxicity of the 14-OH taxoids for proliferating plant cells compared to the 13-OH derivatives.