RESUMO
BACKGROUND: Catheter-associated right atrial thrombus (CRAT) is a recognised complication of central venous catheter (CVC) use for haemodialysis (HD) patients. METHODS: This was a single-centre retrospective longitudinal observational study of consecutive children aged 6 months-18 years over a 7-year period receiving in-centre chronic HD. Echocardiograms as per routine cardiac surveillance were performed 6 months or earlier given clinical concerns. RESULTS: Sixty-five children, 36 boys (55.4%), median (IQR) age 11.8 (5.3, 14.7) years, received HD for kidney failure with replacement therapy (KFRT). Initial modality was HD in 45 (69.2%), with CVC as initial access in 42 (93.3%) and AVF in 3 (6.7%); in the remaining 20 (30.8%) patients PD was the initial modality before switching to HD. Seven of 65 (10.8%) developed CRAT at median 2 (0.8, 8.4) months from CVC insertion, with one CRAT detected 3 days following insertion. One child had 2 episodes of CRAT and one additionally thrombosed their AVF. No patient had an underlying primary kidney disease associated with a pro-thrombotic state. Those with CRAT were younger, had more frequent CVC change and received dialysis for longer duration compared to those with no CRAT. Six episodes of CRAT (75%) received anticoagulation therapy. Infective complications were observed in 25% and catheter malfunction in 50%. Five CRAT episodes (62.5%) resulted in CVC loss. One patient died after a haemorrhagic complication of anticoagulation and sepsis, and another developed life-threatening superior vena cava obstruction syndrome. Overall mortality 14% (1/7). CONCLUSIONS: This is the first report of CRAT in a paediatric HD population. There was ~ 11% incidence of CRAT in patients receiving chronic HD detected by surveillance echocardiography. Although frequently asymptomatic, CRAT is associated with serious sequelae. Anticoagulation and surveillance with expert echocardiography remain mainstays of management. Graphical abstract.
Assuntos
Cateteres de Demora , Trombose , Veia Cava Superior , Anticoagulantes/uso terapêutico , Cateteres de Demora/efeitos adversos , Criança , Humanos , Masculino , Diálise Renal/efeitos adversos , Estudos Retrospectivos , Trombose/epidemiologia , Trombose/etiologiaRESUMO
OBJECTIVES: To understand the effect of attendance at departmental Christmas parties on cohesion and teamwork within the healthcare setting. METHOD DESIGN/SETTING/PARTICIPANTS/INTERVENTIONS/OUTCOME MEASURES: We used the 'Team Development Measure' questionnaire to assess team cohesiveness among healthcare professionals before and after departmental Christmas parties took place. A pooled mean score (PMS) of responses was used to compare between groups. RESULTS: There were no significant differences in perceived measures of team cohesion when comparing responses before (PMSbefore=1.86±0.20) and after (PMSafter=1.91±0.22) the departmental Christmas party (p=0.37), nor was there a significant difference when comparing responses from attendees (PMSbefore=1.83±0.23, PMSafter=1.89±0.24, p=0.52) or non-attendees (PMSbefore=1.84±1.47, PMSafter=1.83±0.15, p=0.91). No difference was observed between professional groups (PMSdoctors=1.85±0.23, PMSnurses=1.95±0.18, p=0.064). CONCLUSION: Attendance at departmental Christmas parties does not seem to result in improved team cohesion.