Detalhe da pesquisa
1.
Population pharmacokinetics of lisinopril in hypertensive children and adolescents with normal to mildly reduced kidney function.
Br J Clin Pharmacol
; 90(2): 504-515, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37864281
2.
Predictive Performance of Physiologically Based Pharmacokinetic Modelling of Beta-Lactam Antibiotic Concentrations in Adipose, Bone, and Muscle Tissues.
Drug Metab Dispos
; 51(4): 499-508, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36639242
3.
Comparison of monoclonal antibody disposition predictions using different physiologically based pharmacokinetic modelling platforms.
J Pharmacokinet Pharmacodyn
; 2023 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37952005
4.
General clinical and methodological considerations on the extrapolation of pharmacokinetics and optimization of study protocols for small molecules and monoclonal antibodies in children.
Br J Clin Pharmacol
; 88(12): 4985-4996, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36256514
5.
Ontogeny and Cross-species Comparison of Pathways Involved in Drug Absorption, Distribution, Metabolism, and Excretion in Neonates (Review): Kidney.
Drug Metab Dispos
; 48(5): 353-367, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32114509
6.
Survey by TEDDY European Network of Excellence for Paediatric Clinical Research demonstrates potential for Europe-wide trials.
Acta Paediatr
; 109(3): 607-612, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31532836
7.
Development of an in Vivo Lipopolysaccharide Inflammation Model to Study the Pharmacodynamics of COX-2 Inhibitors Celecoxib, Mavacoxib, and Meloxicam in Cockatiels (Nymphicus hollandicus).
J Avian Med Surg
; 33(4): 349-360, 2019 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31833303
8.
Development and validation of an UPLC-MS/MS method for the determination of irinotecan (CPT-11), SN-38 and SN-38 glucuronide in human plasma and peritoneal tumor tissue from patients with peritoneal carcinomatosis.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1233: 123980, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38215697
9.
Predicting Volume of Distribution in Neonates: Performance of Physiologically Based Pharmacokinetic Modelling.
Pharmaceutics
; 15(9)2023 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37765316
10.
The Use of Population Pharmacokinetics to Extrapolate Food Effects from Human Adults and Beagle Dogs to the Pediatric Population Illustrated with Paracetamol as a Test Case.
Pharmaceuticals (Basel)
; 17(1)2023 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38256887
11.
Building a Human Physiologically Based Pharmacokinetic Model for Aflatoxin B1 to Simulate Interactions with Drugs.
Pharmaceutics
; 15(3)2023 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36986755
12.
CO2-Driven Nebulization of pH-Sensitive Supramolecular Polymers for Intraperitoneal Hydrogel Formation and the Treatment of Peritoneal Metastasis.
ACS Appl Mater Interfaces
; 15(42): 49022-49034, 2023 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37819736
13.
Unravelling the pharmacokinetics of aflatoxin B1: In vitro determination of Michaelis-Menten constants, intrinsic clearance and the metabolic contribution of CYP1A2 and CYP3A4 in pooled human liver microsomes.
Front Microbiol
; 13: 988083, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36110298
14.
Altered intravenous drug disposition in people living with cystic fibrosis: A meta-analysis integrating top-down and bottom-up data.
CPT Pharmacometrics Syst Pharmacol
; 11(8): 951-966, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35748042
15.
Phase I study of intraperitoneal aerosolized nanoparticle albumin based paclitaxel (NAB-PTX) for unresectable peritoneal metastases.
EBioMedicine
; 82: 104151, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35843174
16.
Desmopressin oral lyophilisate in young children: new insights in pharmacokinetics and pharmacodynamics.
Arch Dis Child
; 106(6): 597-602, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32737054
17.
Pharmacokinetics in Patients with Cystic Fibrosis: A Systematic Review of Data Published Between 1999 and 2019.
Clin Pharmacokinet
; 59(12): 1551-1573, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32808233
18.
Pediatric Pharmacology of Desmopressin in Children with Enuresis: A Comprehensive Review.
Paediatr Drugs
; 22(4): 369-383, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32507959
19.
Simultaneous Measurement of Glomerular Filtration Rate, Effective Renal Plasma Flow and Tubular Secretion in Different Poultry Species by Single Intravenous Bolus of Iohexol and Para-Aminohippuric Acid.
Animals (Basel)
; 10(6)2020 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32545683
20.
An Integrated Paediatric Population PK/PD Analysis of dDAVP: How do PK Differences Translate to Clinical Outcomes?
Clin Pharmacokinet
; 59(1): 81-96, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31347012