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1.
Cureus ; 16(3): e56929, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38665730

RESUMO

Bone giant cell tumors (GCTs) are rare, non-cancerous tumors that mostly affect the meta-epiphyseal region of long bones in the legs and arms. We are reporting a case of GCT of bone of a 14-year-old male; it usually occurs in the age group of 20-40 years. The presence of multinucleated giant cells and stromal cells in the proximal diaphysis of the left tibia serves as a distinguishing characteristic. The majority of GCTs are benign; they have the potential to induce bone loss and can be locally aggressive. Treatment options often include surgery, and in some cases, medications like denosumab may be used to help shrink the tumor or manage recurrent cases.

2.
Cureus ; 16(6): e61635, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38966460

RESUMO

The type of liver cancer that occurs most frequently is hepatocellular carcinoma (HCC). The majority of cases of HCC are secondary to alcoholic cirrhosis or viral hepatitis. The presence of malignant cells with modest nuclear atypia that resemble normal hepatocytes and the lack of bare nuclei in the smears, which shows the neoplastic hepatocytes' capacity, are characteristics of a well-differentiated HCC plasma membrane to tolerate smearing. We present the case of an 83-year-old male patient with a well-differentiated HCC, who had no etiological factors and no signs of alcohol cirrhotic liver, or any symptoms of liver disease which are the main causes of the HCC.

3.
Cureus ; 16(7): e65149, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-39176351

RESUMO

Poorly differentiated thyroid carcinoma (PDTC) is a rare type of thyroid carcinoma that develops from follicular epithelial cells. In terms of morphology and prognosis, PDTC falls between well-differentiated thyroid carcinoma (WDTC) and anaplastic thyroid carcinoma (ATC). The spectrum of malignant thyroid tumors originating from follicles ranges from the fatal ATC at one end to the indolent WDTC at the other. We present a case of a 19-year-old female patient complaining of swelling on the right side of the neck. Computed tomography revealed a solid cystic lesion within the right lobe of the thyroid gland. The diagnosis of PDTC was made through histopathological examination. In this case, we evaluated the histological characteristics of the right lobe of the thyroid gland and presented a case report of PDTC in a young female.

4.
Cureus ; 16(4): e59001, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38800331

RESUMO

A metastatic condition involving signet ring cells rich in mucin is the Krukenberg tumor, which affects the ovaries. Usually, the metastatic disease does not include both ovaries and usually originates from the stomach side, while it can also occur less frequently from other locations. Krukenberg tumors are uncommon in younger age groups and usually occur after the age of 40. We report a case of a 34-year-old female patient with a primary form of past medical history. The patient was treated with multiple rounds of chemotherapy.

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