Detalhe da pesquisa
1.
Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells.
Cell
; 149(6): 1284-97, 2012 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22632761
2.
RPL22 is a tumor suppressor in MSI-high cancers and a key splicing regulator of MDM4.
bioRxiv
; 2023 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38106152
3.
Massively parallel phenotyping of coding variants in cancer with Perturb-seq.
Nat Biotechnol
; 40(6): 896-905, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35058622
4.
Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational state.
Nat Commun
; 13(1): 3778, 2022 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35773251
5.
SMAD4 represses FOSL1 expression and pancreatic cancer metastatic colonization.
Cell Rep
; 36(4): 109443, 2021 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34320363
6.
The Pea3 Ets transcription factor regulates differentiation of multipotent progenitor cells during mammary gland development.
Dev Biol
; 325(1): 106-21, 2009 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18977342
7.
Rhabdoid Tumors Are Sensitive to the Protein-Translation Inhibitor Homoharringtonine.
Clin Cancer Res
; 26(18): 4995-5006, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32631955
8.
Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism.
Sci Rep
; 10(1): 5324, 2020 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32210275
9.
MDM2 and MDM4 Are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors.
Cancer Res
; 79(9): 2404-2414, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30755442
10.
CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer.
Cell Rep
; 29(8): 2355-2370.e6, 2019 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31747605
11.
A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies.
Science
; 365(6453): 599-604, 2019 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31395785
12.
Mutational processes shape the landscape of TP53 mutations in human cancer.
Nat Genet
; 50(10): 1381-1387, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30224644
13.
An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer.
Elife
; 72018 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30059005
14.
Author Correction: Massively parallel phenotyping of coding variants in cancer with Perturb-seq.
Nat Biotechnol
; 40(11): 1691, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36258042
15.
PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer.
Cancer Res
; 77(17): 4613-4625, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28655788
16.
Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer.
Oncotarget
; 7(33): 53137-53152, 2016 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27447971
17.
Integrative radiogenomic profiling of squamous cell lung cancer.
Cancer Res
; 73(20): 6289-98, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23980093
18.
Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers.
Cancer Discov
; 3(9): 1044-57, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23764425
19.
Small molecule antagonists of the Wnt/ß-catenin signaling pathway target breast tumor-initiating cells in a Her2/Neu mouse model of breast cancer.
PLoS One
; 7(3): e33976, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22470504