Detalhe da pesquisa
1.
Clinical validation of the novel HDAC6 radiotracer [18F]EKZ-001 in the human brain.
Eur J Nucl Med Mol Imaging
; 48(2): 596-611, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32638097
2.
Class I and II histone deacetylase expression is not altered in human amyotrophic lateral sclerosis: Neuropathological and positron emission tomography molecular neuroimaging evidence.
Muscle Nerve
; 60(4): 443-452, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31241177
3.
Overlapping and Divergent Actions of Structurally Distinct Histone Deacetylase Inhibitors in Cardiac Fibroblasts.
J Pharmacol Exp Ther
; 361(1): 140-150, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28174211
4.
The bromodomain of Gcn5 regulates site specificity of lysine acetylation on histone H3.
Mol Cell Proteomics
; 13(11): 2896-910, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25106422
5.
A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions.
Mol Cell Proteomics
; 13(11): 2883-95, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25104842
6.
[11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease.
Nat Commun
; 13(1): 4171, 2022 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35853847
7.
In vivo human brain expression of histone deacetylases in bipolar disorder.
Transl Psychiatry
; 10(1): 224, 2020 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32641695
8.
Translation of HDAC6 PET Imaging Using [18F]EKZ-001-cGMP Production and Measurement of HDAC6 Target Occupancy in Nonhuman Primates.
ACS Chem Neurosci
; 11(7): 1093-1101, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32159328
9.
PET neuroimaging reveals histone deacetylase dysregulation in schizophrenia.
J Clin Invest
; 129(1): 364-372, 2019 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30530989
10.
Neuroepigenetic signatures of age and sex in the living human brain.
Nat Commun
; 10(1): 2945, 2019 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31270332
11.
Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia.
ACS Chem Neurosci
; 8(3): 662-668, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27959513
12.
Author Correction: [11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease.
Nat Commun
; 13(1): 5833, 2022 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36192402
13.
Insights into neuroepigenetics through human histone deacetylase PET imaging.
Sci Transl Med
; 8(351): 351ra106, 2016 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27510902
14.
Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis.
Elife
; 3: e02996, 2014 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25161194