Detalhe da pesquisa
1.
Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis.
Mol Cell
; 81(19): 4059-4075.e11, 2021 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34437837
2.
HOXA9 forms a repressive complex with nuclear matrix-associated protein SAFB to maintain acute myeloid leukemia.
Blood
; 141(14): 1737-1754, 2023 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36577137
3.
Unbiased cell surface proteomics identifies SEMA4A as an effective immunotherapy target for myeloma.
Blood
; 139(16): 2471-2482, 2022 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35134130
4.
Cohesin-dependent regulation of gene expression during differentiation is lost in cohesin-mutated myeloid malignancies.
Blood
; 134(24): 2195-2208, 2019 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31515253
5.
BET inhibitor resistance emerges from leukaemia stem cells.
Nature
; 525(7570): 538-42, 2015 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26367796
6.
Glutaminolysis is a metabolic dependency in FLT3ITD acute myeloid leukemia unmasked by FLT3 tyrosine kinase inhibition.
Blood
; 131(15): 1639-1653, 2018 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29463564
7.
CML: new tools to answer old questions.
Blood
; 135(26): 2327-2328, 2020 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32585023
8.
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.
Nature
; 478(7370): 529-33, 2011 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21964340
9.
Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5(+/-) leukemia.
BMC Cancer
; 15: 585, 2015 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26269126
10.
Modeling the evolution of ETV6-RUNX1-induced B-cell precursor acute lymphoblastic leukemia in mice.
Blood
; 118(4): 1041-51, 2011 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21628403
11.
In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis.
Nat Genet
; 55(9): 1542-1554, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37580596
12.
Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death.
Nat Commun
; 14(1): 2132, 2023 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37059720
13.
Preleukemic single-cell landscapes reveal mutation-specific mechanisms and gene programs predictive of AML patient outcomes.
Cell Genom
; 3(12): 100426, 2023 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38116120
14.
Transcriptional variability accelerates preleukemia by cell diversification and perturbation of protein synthesis.
Sci Adv
; 8(31): eabn4886, 2022 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35921412
15.
KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia.
Blood Adv
; 6(1): 165-180, 2022 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34654054
16.
Mutational synergy during leukemia induction remodels chromatin accessibility, histone modifications and three-dimensional DNA topology to alter gene expression.
Nat Genet
; 53(10): 1443-1455, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34556857
17.
Loss of Kat2a enhances transcriptional noise and depletes acute myeloid leukemia stem-like cells.
Elife
; 92020 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31985402
18.
Dissecting the early steps of MLL induced leukaemogenic transformation using a mouse model of AML.
Nat Commun
; 11(1): 1407, 2020 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32179751
19.
Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML.
J Exp Med
; 216(4): 966-981, 2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30890554
20.
Novel and Rare Fusion Transcripts Involving Transcription Factors and Tumor Suppressor Genes in Acute Myeloid Leukemia.
Cancers (Basel)
; 11(12)2019 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31817495