RESUMO
The HUPO Brain Proteome Project (HUPO BPP) held its 20th workshop in Yokohama, Japan, September 15, 2013. The focus of the autumn workshop was on new insights and prospects of neurodegenerative diseases.
Assuntos
Doenças Neurodegenerativas/diagnóstico , Doenças Neurodegenerativas/patologia , Neurologia/educação , Doenças Autoimunes/complicações , Encéfalo/metabolismo , Encéfalo/patologia , Humanos , Japão , Doenças Neurodegenerativas/complicações , Doenças Neurodegenerativas/metabolismo , Proteoma/análise , Proteoma/metabolismo , ProteômicaRESUMO
The HUPO Brain Proteome Project (HUPO BPP) held its 18(th) workshop in Boston, USA, September 12(th) 2012 during the HUPO 11th Annual Word Congress. The focus was on the progress on the Human Brain Proteome Atlas as well as ideas, strategies and methodological aspects.
Assuntos
Proteínas do Tecido Nervoso/análise , Doenças Neurodegenerativas/metabolismo , Proteoma/análise , Proteômica/métodos , Pesquisa Biomédica , Química Encefálica , HumanosRESUMO
The HUPO Brain Proteome Project (HUPO BPP) held its 19th workshop in Dortmund, Germany, from May 22 to 24, 2013. The focus of the spring workshop was on strategies and developments concerning early diagnosis of neurodegenerative diseases.
Assuntos
Biomarcadores/líquido cefalorraquidiano , Pesquisa Biomédica , Encéfalo/patologia , Diagnóstico Precoce , Doenças Neurodegenerativas/diagnóstico , Proteoma/metabolismo , Proteômica , Animais , Encéfalo/metabolismo , Humanos , Imageamento por Ressonância Magnética , Camundongos , Doenças Neurodegenerativas/líquido cefalorraquidiano , RatosRESUMO
The HUPO Brain Proteome Project (HUPO BPP) held its 17(th) workshop in Sao Paulo, Brazil, on May 24 and 25, 2012. The focus was on the progress on the Human Brain Proteome Atlas as well as ideas, strategies and methodological aspects in clinical neuroproteomics.
Assuntos
Biomarcadores/análise , Química Encefálica , Proteínas do Tecido Nervoso/análise , Proteoma/análise , Proteômica/métodos , Animais , Pesquisa Biomédica , HumanosRESUMO
The HUPO Brain Proteome Project (HUPO BPP) held its 16th workshop in Geneva, Switzerland, on September 5, 2011 during the 10th HUPO World Congress. The focus was on launching the Human Brain Proteome Atlas as well as ideas, strategies and methodological aspects in clinical neuroproteomics.
Assuntos
Doenças Neurodegenerativas/metabolismo , Proteômica , Pesquisa Translacional Biomédica/métodos , Encéfalo/metabolismo , HumanosRESUMO
The HUPO Brain Proteome Project (HUPO BPP) held its 15th workshop in Bochum, Germany, from April 8th to 9th, 2011 directly after the Proteomic Forum 2011 in Berlin. Like on every spring workshop, the focus was more on clinical aspects, so that especially clinicians participated in this workshop.
Assuntos
Doenças Neurodegenerativas/metabolismo , Animais , Encéfalo/metabolismo , Humanos , Proteoma/metabolismoRESUMO
The HUPO Brain Proteome Project (HUPO BPP) held its 13th workshop in Ochang from March 30th to 31st, 2010 prior to the Korean HUPO 10th Annual International Proteomics Conference. The principal aim of this project is to obtain a better understanding of neurodiseases and aging with the ultimate objective of discovering prognostic and diagnostic biomarkers, in addition to the development of novel diagnostic techniques and new medications. The attendees came together to discuss progress in the clinical neuroproteomics of human and to define the needs and guidelines required for more advanced proteomics approaches.
Assuntos
Atlas como Assunto , Química Encefálica , Encéfalo/metabolismo , Congressos como Assunto , Proteoma , Proteômica/métodos , Biomarcadores/metabolismo , Biologia Computacional/métodos , Humanos , República da CoreiaRESUMO
The HUPO Brain Proteome Project (HUPO BPP) held its 14th workshop during the HUPO 9th Annual World Congress in Sydney, Australia. The principal aim of this project is to discover prognostic and diagnostic biomarkers associated with neurodegenerative diseases and brain aging, with the ultimate objective of obtaining a better understanding of these conditions and creating roads for the development of novel diagnostic techniques and effective treatments. The attendees came together to discuss progress in the human clinical neuroproteomics and to define the needs and guidelines required for more advanced proteomics approaches.
Assuntos
Encéfalo/metabolismo , Doenças Neurodegenerativas/metabolismo , Proteoma/metabolismo , Proteômica , Atlas como Assunto , Química Encefálica , Bases de Dados de Proteínas , HumanosRESUMO
The HUPO Brain Proteome Project (HUPO BPP) held its 12th workshop in Toronto on 26 September 2009 prior to the HUPO VIII World Congress. The principal aim of this project is to obtain a better understanding of neurodiseases and ageing, with the ultimate objective of discovering prognostic and diagnostic biomarkers, in addition to the development of novel diagnostic techniques and new medications. The attendees came together to discuss progress in the human clinical neuroproteomics and to define the needs and guidelines required for more advanced proteomic approaches.
Assuntos
Encéfalo/metabolismo , Proteômica/métodos , Encéfalo/patologia , Canadá , Humanos , Doenças Neurodegenerativas/metabolismoRESUMO
Several projects were initiated by the Human Proteome Organisation (HUPO) focusing on the proteome analysis of distinct human organs. The initiative dedicated to the brain, its development and correlated diseases is the HUPO Brain Proteome Project (HUPO BPP). An objective data submission, storage, and reprocessing strategy have been established with the help of the results gained in a pilot study phase and within subsequent studies. The bioinformatic relevance of the data is drawn from the inter-laboratory comparisons as well as from the recalculation of all data sets submitted by the different groups. In the following, results of the single groups as well as the centralised reprocessing effort are summarised, demonstrating the added-value of this concerted work.