Detalhe da pesquisa
1.
Two cases of severe pulmonary toxicity from highly active mesothelin-directed CAR T cells.
Mol Ther
; 31(8): 2309-2325, 2023 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37312454
2.
Interaction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondin.
EMBO Rep
; 14(12): 1120-6, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24165923
3.
Clearance of plasma PCSK9 via the asialoglycoprotein receptor mediated by heterobifunctional ligands.
Cell Chem Biol
; 30(1): 97-109.e9, 2023 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36626903
4.
Preclinical discovery and initial clinical data of WVT078, a BCMA × CD3 bispecific antibody.
Leukemia
; 37(6): 1349-1360, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37024520
5.
A CRISPR Screen Reveals Resistance Mechanisms to CD3-Bispecific Antibody Therapy.
Cancer Immunol Res
; 9(1): 34-49, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33177106
6.
PAX8 lineage-driven T cell engaging antibody for the treatment of high-grade serous ovarian cancer.
Sci Rep
; 11(1): 14841, 2021 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34290299
7.
Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells.
Nat Med
; 27(5): 842-850, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33888899
8.
Biophysical investigation of the mode of inhibition of tetramic acids, the allosteric inhibitors of undecaprenyl pyrophosphate synthase.
Biochemistry
; 49(25): 5366-76, 2010 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-20476728
9.
Discovery of Potent and Selective Antibody-Drug Conjugates with Eg5 Inhibitors through Linker and Payload Optimization.
ACS Med Chem Lett
; 10(12): 1674-1679, 2019 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31857845
10.
Pre-clinical validation of B cell maturation antigen (BCMA) as a target for T cell immunotherapy of multiple myeloma.
Oncotarget
; 9(40): 25764-25780, 2018 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29899820
11.
Affinity-Tuned ErbB2 or EGFR Chimeric Antigen Receptor T Cells Exhibit an Increased Therapeutic Index against Tumors in Mice.
Cancer Res
; 75(17): 3596-607, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26330166
12.
Short-term exposure to low-dose ritonavir impairs clearance and enhances adverse effects of trazodone.
J Clin Pharmacol
; 43(4): 414-22, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12723462
13.
Methylation of p53 by Set7/9 mediates p53 acetylation and activity in vivo.
Mol Cell
; 29(3): 392-400, 2008 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18280244
14.
Interaction of triazolam and ketoconazole in P-glycoprotein-deficient mice.
Drug Metab Dispos
; 32(8): 800-4, 2004 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15258104
15.
Microsomal protein concentration modifies the apparent inhibitory potency of CYP3A inhibitors.
Drug Metab Dispos
; 30(12): 1441-5, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12433817
16.
In vitro, pharmacokinetic, and pharmacodynamic interactions of ketoconazole and midazolam in the rat.
J Pharmacol Exp Ther
; 302(3): 1228-37, 2002 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12183684