Detalhe da pesquisa
1.
Metformin's effectiveness in preventing prednisone-induced hyperglycemia in hematological cancers.
J Oncol Pharm Pract
; 26(4): 823-834, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-31495292
2.
Crystal Structures and Cytotoxicity of ent-Kaurane-Type Diterpenoids from Two Aspilia Species.
Molecules
; 23(12)2018 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30518152
3.
Antibiotic prescribing practices in community and clinical settings during the COVID-19 pandemic in Nairobi, Kenya.
PLOS Glob Public Health
; 4(4): e0003046, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38662675
4.
MAIP: An Open-Source Tool to Enrich High-Throughput Screening Output and Identify Novel, Druglike Molecules with Antimalarial Activity.
ACS Med Chem Lett
; 14(12): 1733-1741, 2023 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38116432
5.
Synthesis, biological evaluation and mechanistic studies of totarol amino alcohol derivatives as potential antimalarial agents.
Bioorg Med Chem
; 20(2): 893-902, 2012 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22196513
6.
Replenishing the malaria drug discovery pipeline: Screening and hit evaluation of the MMV Hit Generation Library 1 (HGL1) against asexual blood stage Plasmodium falciparum, using a nano luciferase reporter read-out.
SLAS Discov
; 27(6): 337-348, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35872229
7.
Exploring a Tetrahydroquinoline Antimalarial Hit from the Medicines for Malaria Pathogen Box and Identification of its Mode of Resistance as PfeEF2.
ChemMedChem
; 17(22): e202200393, 2022 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36129427
8.
How can natural products serve as a viable source of lead compounds for the development of new/novel anti-malarials?
Malar J
; 10 Suppl 1: S2, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21411013
9.
Antiplasmodial and antitumor activity of dihydroartemisinin analogs derived via the aza-Michael addition reaction.
Bioorg Med Chem Lett
; 21(10): 2882-6, 2011 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21489789
10.
Synthesis, antimalarial and antitubercular activity of acetylenic chalcones.
Bioorg Med Chem Lett
; 20(3): 942-4, 2010 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20045640
11.
Design, synthesis and in vitro antimalarial evaluation of triazole-linked chalcone and dienone hybrid compounds.
Bioorg Med Chem
; 18(23): 8243-56, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21044845
12.
Examination of WHO/INRUD Core Drug Use Indicators at Public Primary Healthcare Centers in Kisii County, Kenya.
Adv Pharmacol Pharm Sci
; 2020: 3173847, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32647831
13.
Prescription patterns and adequacy of blood pressure control among adult hypertensive patients in Kenya; findings and implications.
Expert Rev Clin Pharmacol
; 10(11): 1263-1271, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28831829
14.
Computer-Aided Drug Discovery Approaches against the Tropical Infectious Diseases Malaria, Tuberculosis, Trypanosomiasis, and Leishmaniasis.
ACS Infect Dis
; 2(1): 8-31, 2016 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27622945
15.
Effects of highly active novel artemisinin-chloroquinoline hybrid compounds on ß-hematin formation, parasite morphology and endocytosis in Plasmodium falciparum.
Biochem Pharmacol
; 82(3): 236-47, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21596024
16.
Enone- and chalcone-chloroquinoline hybrid analogues: in silico guided design, synthesis, antiplasmodial activity, in vitro metabolism, and mechanistic studies.
J Med Chem
; 54(10): 3637-49, 2011 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21500839
17.
Chloroquine resistance: proposed mechanisms and countermeasures.
Curr Drug Deliv
; 7(4): 312-23, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20695842
18.
Extracting molecular information from African natural products to facilitate unique African-led drug-discovery efforts.
Future Med Chem
; 3(3): 257-61, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21446839